Residential delivery area · Missouri
ZIP Code 63645: Fredericktown, MO
ZIP code 63645 uses the postal name Fredericktown, Missouri and lies mostly in Madison County (87% of its land), reaching into St. Francois County and Ste. Genevieve County (Census 2020 ZIP-county file). About 12,000 people live there (Census Bureau, ACS 2020-2024). Median household income is $54,747 (Census Bureau, ACS 2020-2024). By Census place, its land lies in Fredericktown (1%), Mine La Motte (under 1%), Cherokee Pass (under 1%), Junction City (under 1%) and Cobalt (0%); 97% is outside any Census place.
- ACS2020-24
- Census2020
- FHFA2025
- ZBP2023
- IRS2022
- Town
- Fredericktown · its only residential ZIP
- County
- Madison County (87%); St. Francois County (8%); Ste. Genevieve County (4%)
- Census places
- Fredericktown (1%); Mine La Motte (under 1%) census-designated place; Cherokee Pass (under 1%) census-designated place; Junction City (under 1%)
- House district
- MO-8 119th Congress
- State
- Missouri
- Time zone
- Central
- Land area
- 359.3 sq mi · 32 people per sq mi
Where is ZIP code 63645?
63645 centers on 37.543°, -90.326° and covers 359.3 square miles of land plus 2.5 of water. It borders 11 ZIP codes: 63655, 63621, 63640, 63662, 63637, 63650, 63620, 63964, 63670, 63775 and more.
The map draws ZIP code areas only. For the streets inside 63645, open its center on OpenStreetMap.
Source: U.S. Census Bureau, 2020 ZCTA cartographic boundaries and the 2023 Gazetteer (2020 ZCTAs); ZIP-to-county shares, Census places and House districts (119th Congress) from the Census 2020 relationship files (shares of land); metro area from the OMB delineation (July 2023); town name and time zone from simplemaps US ZIP Codes (CC BY 4.0).
How does 63645 compare with the rest of Madison County?
| Measure | 63645 | In Madison County | In MO |
|---|---|---|---|
| People (ACS 2020-2024) | 11,554 | 1st of 7 | 169th of 1,035 |
| Median household income | $55k | 2nd of 3 | 366th of 479 |
| Median home value | $158k | 2nd of 3 | 367th of 494 |
Its median household income is higher than in 21% of U.S. residential ZIP codes, and it is denser than 34% of all U.S. residential ZIP codes. ZIP codes at the ACS caps ($250,000 or more for household income, $2,000,000 or more for home value) share the top rank.
Source: U.S. Census Bureau, ACS 2020-2024 5-year estimates (B01003, B19013, B25077); ranks by PlainZIP over residential ZIP codes (ZCTAs).
How many people live in 63645?
The 2020 Census counted 11,991 people in 63645; the ACS, which samples households over 2020-2024, estimates 11,554. Between the 2010 and 2020 censuses its population grew 5.0% (its boundary stayed at least 90% the same).
- People, ACS 2020-2024
- 11,554
- 2020 Census count
- 11,991+5.0% since 2010 (11,420)
- Households
- 4,236
- Median age
- 40.2
Source: U.S. Census Bureau, ACS 2020-2024 5-year estimates (B01003, B01002, B11001); 2020 Census (DHC P1); 2010 Census (SF1 P1).
Who lives in 63645?
Of the 11,554 people the ACS estimates in 63645, 24.4% are under 18 and 19.3% are 65 or older. The largest group by race and Hispanic origin is White (not Hispanic) (92.2%).
- Under 1824.4%
- 18 to 6456.3%
- 65 and older19.3%
- White, not Hispanic92.2%
- Other or two or more4.4%
- Hispanic or Latino2.8%
- Asian, not Hispanic0.3%
- Black, not Hispanic0.3%
Source: U.S. Census Bureau, ACS 2020-2024 5-year estimates (B01001 age by sex, B03002 Hispanic or Latino origin by race); shares of the estimated population, small ZIP codes carry wide margins.
What do households in 63645 earn?
Median household income is $54,747 (ACS 2020-2024), the 2nd highest of the 3 ranked ZIP codes in Madison County. It is not measurably different from 2015-2019 ($54,682 in 2024 dollars): the change is within the surveys' margins of error.
- Median household income
- $54,747
- Income per person
- $31,680
- Below the poverty line
- 12.2%
- Unemployed (of the labor force)
- 4.3%
- Adults 25+ with a bachelor's degree
- 17.5%
- Adjusted gross income per tax return, 2022
- $55,5194,890 returns; wages 69% of AGI (IRS)
Source: U.S. Census Bureau, ACS 2020-2024 and 2015-2019 5-year estimates (B19013, B19301, B17001, B23025, B15003; 2015-2019 dollars converted with the BLS CPI-U, 1.22699); IRS Statistics of Income, ZIP code data, tax year 2022 (adjusted gross income per return, filed under the address on the return).
What are homes worth in 63645?
FHFA's house price index for 63645, built from repeat sales and appraisals of the same homes, rose 75% from 2015 to 2025 and rose 48% from 2020 to 2025, and moved +0.6% in 2025.
- Median home value (owners' estimate)
- $157,500
- Median gross rent
- $811
- Homes owned by their occupants
- 73.1%
- Housing units
- 5,161
Source: U.S. Census Bureau, ACS 2020-2024 5-year estimates (B25077, B25064, B25003, B25001); FHFA House Price Index, annual five-digit ZIP, updated 2026-03-31.
What businesses are in 63645?
217 business establishments had a location in this ZIP code in 2023, 25 fewer than in 2018; the most are in retail trade (ZIP Code Business Patterns).
- Retail trade40
- Construction26
- Health care and social assistance26
- Other services (except public administration)26
- Accommodation and food services24
- Administrative and support and waste management and remediation services15
Source: U.S. Census Bureau, ZIP Code Business Patterns 2023 and 2018 (establishments with paid employees, by the business's ZIP code).
Which ZIP codes are next to 63645?
| ZIP | Town | People | Household income | Distance |
|---|---|---|---|---|
| 63655 | Marquand | 1,639 | $62k | 13.1 mi |
| 63621 | Arcadia | 1,632 | $88k | 14.0 mi |
| 63640 | Farmington | 29,263 | $62k | 14.8 mi |
| 63662 | Patton | 536 | $55k | 15.1 mi |
| 63637 | Doe Run | 759 | $55k | 15.7 mi |
| 63650 | Ironton | 3,600 | $50k | 17.3 mi |
| 63620 | Annapolis | 1,036 | $42k | 21.1 mi |
| 63964 | Silva | 733 | $42k | 21.4 mi |
| 63670 | Sainte Genevieve | 12,293 | $63k | 26.4 mi |
| 63775 | Perryville | 16,325 | $64k | 27.1 mi |
| 63673 | Saint Mary | 2,340 | $78k | 27.6 mi |
| 63663 | Pilot Knob | 649 | $45k | 18.5 mi (near) |
Source: PlainZIP from the Census 2020 ZCTA boundaries (shared edges) and internal points; figures ACS 2020-2024.