Residential delivery area · Maryland

ZIP Code 21758: Knoxville, MD

ZIP code 21758 uses the postal name Knoxville, Maryland and lies mostly in Frederick County (50% of its land) with the rest in Washington County (Census 2020 ZIP-county file). About 4,400 people live there (Census Bureau, ACS 2020-2024). Median household income is $111,528 (Census Bureau, ACS 2020-2024). By Census place, its land lies in Garretts Mill (2%), Rosemont (2%), Sandy Hook (under 1%) and Yarrowsburg (under 1%), and 2% in smaller places; 93% is outside any Census place.

  • ACS2020-24
  • Census2020
  • FHFA2025
  • ZBP2023
  • IRS2022
2national area: Maryland, District of Columbia, North Carolina, South Carolina, Virginia and West Virginia
217sectional center: Baltimore, MD (SCF 212)
58delivery area within it
Town
Knoxville · its only residential ZIP
Census places
Garretts Mill (2%) census-designated place; Rosemont (2%); Sandy Hook (under 1%) census-designated place; Yarrowsburg (under 1%) census-designated place
Metro area
Washington-Arlington-Alexandria, DC-VA-MD-WV
House district
MD-6 119th Congress
Time zone
Eastern
Land area
32.0 sq mi · 138 people per sq mi

Where is ZIP code 21758?

21758 centers on 39.353°, -77.657° and covers 32.0 square miles of land plus 2.8 of water. It borders 8 ZIP codes: 21715, 21716, 21755, 21779, 20180, 25425, 21782, 20132.

20132 · Purcellville20180 · Lovettsville21715 · Brownsville21716 · Brunswick21755 · Jefferson21779 · Rohrersville21782 · Sharpsburg25425 · Harpers Ferry21758 · Knoxville (this ZIP)2175825425217822175520180217792171620132 · Purcellville20180 · Lovettsville21715 · Brownsville21716 · Brunswick21755 · Jefferson21779 · Rohrersville21782 · Sharpsburg25425 · Harpers Ferry21758 · Knoxville (this ZIP)2175825425217822175520180217792171620132 · Purcellville20180 · Lovettsville21715 · Brownsville21716 · Brunswick21755 · Jefferson21779 · Rohrersville21782 · Sharpsburg25425 · Harpers Ferry21758 · Knoxville (this ZIP)217582542521782217552018021779
Shaded by median household income, in national fifths (ACS 2020-2024); 21758 outlined. Census 2020 ZCTA boundaries. <$54.1k$98.1k+no figure

The map draws ZIP code areas only. For the streets inside 21758, open its center on OpenStreetMap.

Source: U.S. Census Bureau, 2020 ZCTA cartographic boundaries and the 2023 Gazetteer (2020 ZCTAs); ZIP-to-county shares, Census places and House districts (119th Congress) from the Census 2020 relationship files (shares of land); metro area from the OMB delineation (July 2023); town name and time zone from simplemaps US ZIP Codes (CC BY 4.0).

How does 21758 compare with the rest of Frederick County?

Rank of 21758 among the residential ZIP codes of its town, county and state (1 = the most; income and home value among ZIP codes of 1,000+ people living in households)
Measure21758In Frederick CountyIn MD
People (ACS 2020-2024)4,40922nd of 35248th of 477
Median household income$112k15th of 26145th of 293
Median home value$425k20th of 28165th of 320

Its median household income is higher than in 87% of U.S. residential ZIP codes, and it is denser than 58% of all U.S. residential ZIP codes. ZIP codes at the ACS caps ($250,000 or more for household income, $2,000,000 or more for home value) share the top rank.

Source: U.S. Census Bureau, ACS 2020-2024 5-year estimates (B01003, B19013, B25077); ranks by PlainZIP over residential ZIP codes (ZCTAs).

How many people live in 21758?

The 2020 Census counted 4,809 people in 21758; the ACS, which samples households over 2020-2024, estimates 4,409. Between the 2010 and 2020 censuses its population fell 2.3% (its boundary stayed at least 90% the same).

People, ACS 2020-2024
4,409±763 (90% margin)
2020 Census count
4,809−2.3% since 2010 (4,921)
Households
1,588
Median age
39.0

Source: U.S. Census Bureau, ACS 2020-2024 5-year estimates (B01003, B01002, B11001); 2020 Census (DHC P1); 2010 Census (SF1 P1).

Who lives in 21758?

Of the 4,409 people the ACS estimates in 21758, 24.2% are under 18 and 17.7% are 65 or older. The largest group by race and Hispanic origin is White (not Hispanic) (81.1%).

  • Under 1824.2%
  • 18 to 6458.1%
  • 65 and older17.7%
Age of the people of 21758 (ACS 2020-2024, B01001)
  • White, not Hispanic81.1%
  • Hispanic or Latino9.0%
  • Other or two or more4.8%
  • Black, not Hispanic2.9%
  • Asian, not Hispanic2.0%
Race and Hispanic origin in 21758 (ACS 2020-2024, B03002); each person counted once

Source: U.S. Census Bureau, ACS 2020-2024 5-year estimates (B01001 age by sex, B03002 Hispanic or Latino origin by race); shares of the estimated population, small ZIP codes carry wide margins.

What do households in 21758 earn?

Median household income is $111,528 (ACS 2020-2024), the 15th highest of the 26 ranked ZIP codes in Frederick County. It is not measurably different from 2015-2019 ($99,233 in 2024 dollars): the change is within the surveys' margins of error.

Median household income
$111,528±$18,951
Income per person
$50,488
Below the poverty line
5.9%
Unemployed (of the labor force)
8.5%
Adults 25+ with a bachelor's degree
43.7%
Adjusted gross income per tax return, 2022
$93,6622,340 returns; wages 72% of AGI (IRS)

Source: U.S. Census Bureau, ACS 2020-2024 and 2015-2019 5-year estimates (B19013, B19301, B17001, B23025, B15003; 2015-2019 dollars converted with the BLS CPI-U, 1.22699); IRS Statistics of Income, ZIP code data, tax year 2022 (adjusted gross income per return, filed under the address on the return).

What are homes worth in 21758?

FHFA's house price index for 21758, built from repeat sales and appraisals of the same homes, rose 89% from 2015 to 2025 and rose 60% from 2020 to 2025, and moved +19.5% in 2025.

Median home value (owners' estimate)
$424,600
Median gross rent
$1,770
Homes owned by their occupants
84.4%
Housing units
1,626
0 100 200 300 19892000201020202025 0 100 200 300 19892000201020202025 0 100 200 300 19892000201020202025
Index = 100 in 1989, the first year FHFA reports for 21758; 2025: 344.3. Annual, not seasonally adjusted; FHFA calls its ZIP-level indexes developmental.

Source: U.S. Census Bureau, ACS 2020-2024 5-year estimates (B25077, B25064, B25003, B25001); FHFA House Price Index, annual five-digit ZIP, updated 2026-03-31.

What businesses are in 21758?

59 business establishments had a location in this ZIP code in 2023, 4 more than in 2018; the most are in construction (ZIP Code Business Patterns).

  • Construction16
  • Other services (except public administration)12
  • Professional, scientific, and technical services10
  • Administrative and support and waste management and remediation services6
  • Retail trade4
  • Accommodation and food services4

Source: U.S. Census Bureau, ZIP Code Business Patterns 2023 and 2018 (establishments with paid employees, by the business's ZIP code).

Which ZIP codes are next to 21758?

ZIP codes that share a boundary with 21758, then the nearest by center
ZIPTownPeopleHousehold incomeDistance
21715Brownsville20–1.8 mi
21716Brunswick7,200$109k2.9 mi
21755Jefferson5,909$137k4.8 mi
21779Rohrersville1,311–4.9 mi
20180Lovettsville, VA7,531$152k5.9 mi
25425Harpers Ferry, WV13,332$94k7.0 mi
21782Sharpsburg3,704$94k9.0 mi
20132Purcellville, VA19,817$182k13.5 mi
21718Burkittsville134$94k3.2 mi (near)
21756Keedysville3,640$102k7.6 mi (near)

Source: PlainZIP from the Census 2020 ZCTA boundaries (shared edges) and internal points; figures ACS 2020-2024.