Residential delivery area · Virginia
ZIP Code 22645: Middletown, VA
ZIP code 22645 uses the postal name Middletown, Virginia and lies mostly in Frederick County (57% of its land) with the rest in Warren County (Census 2020 ZIP-county file). About 4,600 people live there (Census Bureau, ACS 2020-2024). Median household income is $90,875 (Census Bureau, ACS 2020-2024). By Census place, 2% of its land lies in Middletown; 98% is outside any Census place.
- ACS2020-24
- Census2020
- FHFA2025
- ZBP2023
- IRS2022
- Town
- Middletown · its only residential ZIP
- County
- Frederick County (57%); Warren County (43%)
- Census places
- Middletown
- Metro area
- Winchester, VA-WV
- House district
- VA-6 119th Congress
- State
- Virginia
- Time zone
- Eastern
- Land area
- 36.4 sq mi · 128 people per sq mi
- PO Box ZIPs
- 22649 also use the name Middletown
Where is ZIP code 22645?
22645 centers on 39.019°, -78.275° and covers 36.4 square miles of land plus 0.4 of water. It borders 4 ZIP codes: 22655, 22657, 22630, 22602.
The map draws ZIP code areas only. For the streets inside 22645, open its center on OpenStreetMap.
Source: U.S. Census Bureau, 2020 ZCTA cartographic boundaries and the 2023 Gazetteer (2020 ZCTAs); ZIP-to-county shares, Census places and House districts (119th Congress) from the Census 2020 relationship files (shares of land); metro area from the OMB delineation (July 2023); town name and time zone from simplemaps US ZIP Codes (CC BY 4.0).
How does 22645 compare with the rest of Frederick County?
| Measure | 22645 | In Frederick County | In VA |
|---|---|---|---|
| People (ACS 2020-2024) | 4,639 | 7th of 12 | 374th of 903 |
| Median household income | $91k | not ranked | not ranked |
| Median home value | $420k | 2nd of 12 | 158th of 552 |
22645's median household income is not ranked: its 90% margin of error (±$25,806) is more than a quarter of the figure ($90,875). Rankings use ZIP codes of 1,000 or more people living in households, with margins at most 25% of the figure.
It is denser than 57% of U.S. residential ZIP codes. ZIP codes at the ACS caps ($250,000 or more for household income, $2,000,000 or more for home value) share the top rank.
Source: U.S. Census Bureau, ACS 2020-2024 5-year estimates (B01003, B19013, B25077); ranks by PlainZIP over residential ZIP codes (ZCTAs).
How many people live in 22645?
The 2020 Census counted 4,208 people in 22645; the ACS, which samples households over 2020-2024, estimates 4,639. Between the 2010 and 2020 censuses its population grew 8.5% (its boundary stayed at least 90% the same).
- People, ACS 2020-2024
- 4,639±561 (90% margin)
- 2020 Census count
- 4,208+8.5% since 2010 (3,880)
- Households
- 1,828
- Median age
- 43.6
Source: U.S. Census Bureau, ACS 2020-2024 5-year estimates (B01003, B01002, B11001); 2020 Census (DHC P1); 2010 Census (SF1 P1).
Who lives in 22645?
Of the 4,639 people the ACS estimates in 22645, 23.3% are under 18 and 19.9% are 65 or older. The largest group by race and Hispanic origin is White (not Hispanic) (83.5%).
- Under 1823.3%
- 18 to 6456.8%
- 65 and older19.9%
- White, not Hispanic83.5%
- Hispanic or Latino9.8%
- Other or two or more3.3%
- Black, not Hispanic2.8%
- Asian, not Hispanic0.6%
Source: U.S. Census Bureau, ACS 2020-2024 5-year estimates (B01001 age by sex, B03002 Hispanic or Latino origin by race); shares of the estimated population, small ZIP codes carry wide margins.
What do households in 22645 earn?
Median household income is $90,875 (ACS 2020-2024). It is not measurably different from 2015-2019 ($96,542 in 2024 dollars): the change is within the surveys' margins of error.
- Median household income
- $90,875±$25,806
- Income per person
- $47,432
- Below the poverty line
- 7.5%
- Unemployed (of the labor force)
- 1.1%
- Adults 25+ with a bachelor's degree
- 30.3%
- Adjusted gross income per tax return, 2022
- $85,2932,310 returns; wages 73% of AGI (IRS)
Source: U.S. Census Bureau, ACS 2020-2024 and 2015-2019 5-year estimates (B19013, B19301, B17001, B23025, B15003; 2015-2019 dollars converted with the BLS CPI-U, 1.22699); IRS Statistics of Income, ZIP code data, tax year 2022 (adjusted gross income per return, filed under the address on the return).
What are homes worth in 22645?
FHFA's house price index for 22645, built from repeat sales and appraisals of the same homes, rose 78% from 2015 to 2025 and rose 53% from 2020 to 2025, and moved +1.8% in 2025.
- Median home value (owners' estimate)
- $419,900
- Median gross rent
- $1,019
- Homes owned by their occupants
- 80.4%
- Housing units
- 1,942
Source: U.S. Census Bureau, ACS 2020-2024 5-year estimates (B25077, B25064, B25003, B25001); FHFA House Price Index, annual five-digit ZIP, updated 2026-03-31.
What businesses are in 22645?
79 business establishments had a location in this ZIP code in 2023, 14 more than in 2018; the most are in construction (ZIP Code Business Patterns).
- Construction19
- Retail trade13
- Other services (except public administration)10
- Real estate and rental and leasing7
- Professional, scientific, and technical services7
- Wholesale trade6
Source: U.S. Census Bureau, ZIP Code Business Patterns 2023 and 2018 (establishments with paid employees, by the business's ZIP code).
Which ZIP codes are next to 22645?
| ZIP | Town | People | Household income | Distance |
|---|---|---|---|---|
| 22655 | Stephens City | 22,687 | $109k | 4.8 mi |
| 22657 | Strasburg | 12,067 | $64k | 5.3 mi |
| 22630 | Front Royal | 35,615 | $85k | 8.1 mi |
| 22602 | Winchester | 32,840 | $101k | 8.7 mi |
| 22641 | Strasburg | 165 | $136k | 7.8 mi (near) |
| 22663 | White Post | 1,705 | $135k | 9.0 mi (near) |
| 22660 | Toms Brook | 1,468 | $68k | 9.9 mi (near) |
| 22654 | Star Tannery | 1,040 | $75k | 10.7 mi (near) |
Source: PlainZIP from the Census 2020 ZCTA boundaries (shared edges) and internal points; figures ACS 2020-2024.
Which other ZIP codes use the name Middletown?
1 more ZIP code carries the postal name Middletown, VA without a residential delivery area: PO boxes at the post office, or a single organization with its own ZIP code. The Census Bureau publishes no figures for it.
| ZIP | County |
|---|---|
| 22649 | Frederick County |
Source: GeoNames postal codes (CC BY 4.0), downloaded 2026-10-09; a ZIP code with no Census ZCTA has no residential delivery area.