Indianapolis, IN · standard
ZIP Code 46221
Marion County, Indiana - Census ACS demographics, housing tenure, and business patterns, benchmarked against every US ZIP.
- 26,393
- 511/sq mi High-density area
- $65,280
- Median income Near-median income area
- $191,300
- Median home value Near-median home value
- 16.0%
- Bachelor's or higher Below-average bachelor's attainment
National ZIP placement
Indianapolis pairs a below-median household income with below-median home values, in a low-density, homeowner-dominated area.
- 39th pct
- household income, US ZIPs
- 41st pct
- home value, US ZIPs
- 511
- people per sq mi
- 62%
- owner-occupied homes
Source: U.S. Census Bureau ACS 5-Year Estimates (2019–2023). Percentiles rank ZIP 46221 against every reporting US ZIP.
FHFA HPI release change
What changed in the latest House Price Index year
- FHFA House Price Index values in ZIP 46221 (Indianapolis, IN) rose +9.1% from 2023 to 2024. The all-transactions index moved from 200.6 in 2023 to 218.9 in 2024 (2000 = 100).
ZIP code 46221 is a densely settled ZIP (a standard USPS delivery area) in Indianapolis, Marion County, Indiana, with 26,393 residents across 51.6 square miles, a density of 511 people per square mile, in the Indiana/Indianapolis time zone.
ZIP 46221 reports a modest median household income of $65,280 (11% below the average Indiana ZIP), while per-capita income is $29,663. The poverty rate is 18.4%, with unemployment at 6.1%; those measures add context to the income figure. Median home value is $191,300 (1% below the average Indiana ZIP) and median rent is $1,137; 61.8% of occupied homes are owner-occupied.
Educational attainment sits below the national norm: 16.0% of adults hold a bachelor's degree or higher, the median age is 34.5, and the average commute is 27 minutes. The page also surfaces 10 ZIP codes within roughly 10 miles and 6 more in Marion County, so 46221 can be compared with both its immediate and county-level context.
Every figure on this page is sourced from the U.S. Census Bureau American Community Survey 5-Year Estimates (including median rent) and the FHFA House Price Index, no estimates, no proprietary scoring. Verify with Census →
Top industries in ZIP 46221
Top 5 sectors by establishment count in Indianapolis, IN
Which industries have the most business establishments in ZIP 46221.
- Retail trade
Retail trade
47 establishments
- Construction
Construction
43 establishments
- Health care and social assistance
Health care and social assistance
37 establishments
- Other services (except public administration)
Other services (except public administration)
36 establishments
- Transportation and warehousing
Transportation and warehousing
29 establishments
What this shows Establishment counts come from the Census ZIP Code Business Patterns program, which counts physical business locations rather than employees or revenue.
Source: U.S. Census Bureau, American Community Survey 5-Year Estimates + ZIP Code Business Patterns + FHFA HPI ACS demographics and median rent, ZBP business establishments, FHFA HPI for ZIP 46221, Indianapolis, IN · 2023 Census ACS 5-Year Estimates use a rolling 60-month sample for stable small-geography estimates; ZBP updated annually; FHFA HPI updated quarterly/annually.
Quick Facts
26,393
Population
51.6
Area (sq mi)
511
People / sq mi
Indiana/Indianapolis
Time Zone
standard
ZIP Type
Who lives in ZIP 46221?
34.5
Median Age
50.1%
Male
49.9%
Female
10.6%
Foreign-Born
Hispanic or Latino is an ethnicity category from the Census Bureau and may overlap with other categories above.
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
How much do residents earn?
$65,280
Median Household Income
-11% vs state ZIP avg
$29,663
Per Capita Income
18.4%
Poverty Rate
6.1%
Unemployment Rate
27.1 min
Mean Commute Time
How ZIP 46221 ranks among Indiana ZIPs
Indianapolis, IN household income vs. every Indiana ZIP code
Median household income among 721 reporting Indiana ZIPs (this ZIP's population is too small for a reliable national-corpus placement)
$65,280 37th percentile higher than 37% of 721 Indiana ZIPs
Each bar is a $20K-wide band; taller bars hold more Indiana ZIPs. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.
Source U.S. Census Bureau, ACS 5-Year Estimates · 2019–2023
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
What is the education profile here?
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
What does housing look like?
Housing stock: occupied vs vacant
11,140housing units
11,140
Total Housing Units
10,117
Occupied Units
1,023
Vacant Units
2.66
Avg Household Size
Occupancy Type
$191,300
Median Home Value
-1% vs state ZIP avg
$1,137
Median Rent
1976
Median Year Built
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
How have home values changed over time?
FHFA House Price Index, annual appreciation data based on repeat sales and appraisals
+9.1%
YoY Change (2024)
219
HPI Index (2000 = 100)
+119%
Total Change Since 2000
Home values in ZIP 46221 have increased 9.1% over the past year (2024). Since 2000, this ZIP has seen +119% cumulative appreciation.
| Year | Annual Change | HPI Index |
|---|---|---|
| 2020 | +5.6% | 139 |
| 2021 | +15.5% | 160 |
| 2022 | +14.1% | 183 |
| 2023 | +9.7% | 201 |
| 2024 | +9.1% | 219 |
Source: Federal Housing Finance Agency (FHFA) House Price Index, All-Transactions, Five-Digit ZIP Codes (Developmental Index). Index base = 100 in year 2000. Data through 2024. ZIP codes with few transactions may show missing values.
What businesses operate in this ZIP?
Census Bureau data shows 341 business establishments in ZIP 46221, employing approximately 10,775 people with a combined annual payroll of $1,263,921,000.
341
Businesses
10,775
Employees
$1.3B
Annual Payroll
15
Industry Sectors
| Industry | Establishments | % of Total |
|---|---|---|
| Retail trade | 47 | 13.8% |
| Construction | 43 | 12.6% |
| Health care and social assistance | 37 | 10.8% |
| Other services (except public administration) | 36 | 10.6% |
| Transportation and warehousing | 29 | 8.5% |
| Accommodation and food services | 29 | 8.5% |
| Wholesale trade | 27 | 7.9% |
| Administrative and support and waste management and remediation services | 26 | 7.6% |
| Real estate and rental and leasing | 21 | 6.2% |
| Manufacturing | 12 | 3.5% |
| Information | 9 | 2.6% |
| Professional, scientific, and technical services | 9 | 2.6% |
| Finance and insurance | 6 | 1.8% |
| Utilities | 3 | 0.9% |
| Management of companies and enterprises | 3 | 0.9% |
Source: U.S. Census Bureau, ZIP Code Business Patterns (ZBP), 2023. Employment figures may include noise for disclosure avoidance.
Nearby ZIP Codes
Want a side-by-side? Compare 46221 vs 46241 →
ZIP 46221 vs its nearest neighbors, by population
Resident population of this ZIP and the closest reporting ZIP codes within ~10 miles.
- 46227
Indianapolis (46227)
57,086 residents
- 46224
Indianapolis (46224)
35,094 residents
- 46222
Indianapolis (46222)
34,044 residents
- 46241
Indianapolis (46241)
30,670 residents
- 46142
Greenwood (46142)
30,413 residents
- 46217
Indianapolis (46217)
29,358 residents
- 46221
Indianapolis (46221)
26,393 residents
- 46113 14,063
Camby (46113)
14,063 residents
- 46231 10,440
Indianapolis (46231)
10,440 residents
What this shows Among its immediate neighbors, ZIP 46221 ranks #7 by population - useful context the national average alone can't give.
ZIP 46221 vs its nearest neighbors, by median income
Median household income of this ZIP and the closest reporting ZIP codes within ~10 miles.
- 46217
Indianapolis (46217)
$92,029 median income
- 46142
Greenwood (46142)
$89,001 median income
- 46113
Camby (46113)
$84,463 median income
- 46231
Indianapolis (46231)
$71,825 median income
- 46221
Indianapolis (46221)
$65,280 median income
- 46224
Indianapolis (46224)
$55,986 median income
- 46225
Indianapolis (46225)
$55,190 median income
- 46241
Indianapolis (46241)
$53,653 median income
- 46227
Indianapolis (46227)
$53,629 median income
What this shows By household income, ZIP 46221 ranks #5 of 9 neighboring ZIPs, local affluence varies block to block, not just metro to metro.
| ZIP Code | City | Population | Distance |
|---|---|---|---|
| 46241 | Indianapolis, IN | 30,670 | 2.8 mi |
| 46217 | Indianapolis, IN | 29,358 | 2.7 mi |
| 46183 | West Newton, IN | 82 | 3.6 mi |
| 46231 | Indianapolis, IN | 10,440 | 4.8 mi |
| 46222 | Indianapolis, IN | 34,044 | 7.0 mi |
| 46224 | Indianapolis, IN | 35,094 | 7.2 mi |
| 46227 | Indianapolis, IN | 57,086 | 5.8 mi |
| 46225 | Indianapolis, IN | 7,319 | 5.2 mi |
| 46113 | Camby, IN | 14,063 | 5.4 mi |
| 46142 | Greenwood, IN | 30,413 | 5.9 mi |
Nationwide ZIPs with similar ACS profiles
Two Census-derived peer sets for ZIP 46221, both outside IN so the neighborhoods are not geographic containment (Nearby and same-county blocks stay local).
Similar population
Nearest cross-state ZIPs by resident population (26,393 here; floor ≥1,000).
Similar median household income
Nearest cross-state ZIPs by ACS median household income.
More ZIP Codes in Marion County
Related Areas
Frequently Asked Questions
What county is ZIP code 46221 in?
ZIP code 46221 (Indianapolis) is located in Marion County, Indiana. Marion County contains multiple ZIP codes, see the full list at /counties/marion-in.
What is the population of ZIP code 46221?
ZIP code 46221 in Indianapolis, IN has a population of 26,393 according to the Census Bureau ACS 2023 estimates.
What is the median household income in ZIP 46221?
The median household income in ZIP 46221 is $65,280, which is 14% below the national average of $76,288.
What is the average home value in ZIP 46221?
The median home value in ZIP 46221 is $191,300, which is 31% below the national average of $278,155.
What is the demographic makeup of ZIP 46221?
The largest racial group in ZIP 46221 is White at 68.1%. Hispanic or Latino residents make up 13.2% of the population.
How many businesses are in ZIP code 46221?
ZIP code 46221 has 341 business establishments employing approximately 10,775 people, according to Census Bureau ZIP Code Business Patterns (ZBP) 2023 data.
What are the main industries in ZIP code 46221?
The top industries by establishment count in ZIP 46221 are: Retail trade (47), Construction (43), Health care and social assistance (37). There are 15 industry sectors represented in total.
How have home values changed in ZIP code 46221?
According to the FHFA House Price Index, home values in ZIP 46221 increased by 9.1% in 2024. Since 2000, home values in this ZIP have appreciated by approximately 119%. This is a developmental index based on repeat sales and appraisal data from Fannie Mae and Freddie Mac.
What is the education level in ZIP code 46221?
In ZIP code 46221, 52.4% of residents aged 25+ have a high school diploma or higher, and 16.0% hold a bachelor's degree or higher. These figures come from the Census Bureau ACS 5-Year Estimates (2023).
What is the average commute time in ZIP 46221?
The mean commute time for workers in ZIP code 46221 is 27.1 minutes according to Census ACS data. The national average is roughly 26 minutes, so commuters here spend more time traveling to work than typical.
What percentage of residents own vs. rent in ZIP 46221?
In ZIP code 46221, approximately 61.8% of occupied housing units are owner-occupied and 38.2% are renter-occupied, based on Census ACS 2023 data.
What is the poverty rate in ZIP code 46221?
The poverty rate in ZIP code 46221 is 18.4% according to Census Bureau ACS 2023 estimates. This measures the percentage of the population living below the federal poverty threshold.
Related
Take this with you
What to do with ZIP 46221's numbers, next.
- See how ZIP 46221 compares to a neighboring ZIP code on the same Census fields Compare this ZIP
- Check where Indianapolis, IN ranks among every U.S. ZIP code on income, education, or homeownership View national rankings
- Save this ZIP to your shortlist to track alongside others you're considering View your shortlist
ZIP Code Tabulation Areas (ZCTAs) are Census Bureau approximations of USPS ZIP codes; figures describe the ZCTA area, not any single address within it.