Indianapolis, IN · standard
ZIP Code 46221
Marion County, Indiana - Census ACS demographics, housing tenure, and business patterns, benchmarked against every US ZIP.
- 26,393
- 511/sq mi
- $65,280
- Median income
- $191,300
- Median home value
- 16.0%
- Bachelor's or higher
The verdict
Indianapolis pairs a below-median household income with below-median home values, in a low-density, homeowner-dominated area.
- 39th pct
- household income, US ZIPs
- 41th pct
- home value, US ZIPs
- 511
- people per sq mi
- 62%
- owner-occupied homes
Source: U.S. Census Bureau ACS 5-Year Estimates (2019–2023). Percentiles rank ZIP 46221 against every reporting US ZIP.
ZIP code 46221 is a densely settled ZIP (a standard USPS delivery area) in Indianapolis, Marion County, Indiana, with 26,393 residents across 51.6 square miles, a density of 511 people per square mile, in the Indiana/Indianapolis time zone.
ZIP 46221 reports a modest median household income of $65,280 (11% below the Indiana average), while per-capita income is $29,663. 18.4% of residents live below the poverty line, and the unemployment rate reads 6.1%. Median home value sits at $191,300 (1% below the state average), median rent at $1,137 a month, and owner-occupancy at 61.8%.
Educational attainment sits below the national norm: 16.0% of adults hold a bachelor's degree or higher, the median age is 34.5, and the average commute is 27 minutes. A geography-based comparison follows: 10 ZIP codes within about 10 miles of 46221, plus 6 more within Marion County, give a clearer read than the national average alone.
Every figure on this page is sourced from the U.S. Census Bureau American Community Survey 5-Year Estimates (including median rent) and the FHFA House Price Index, no estimates, no proprietary scoring. Verify with Census →
Top industries in ZIP 46221
Top 5 sectors by establishment count in Indianapolis, IN
Which industries have the most business establishments in ZIP 46221.
- Retail trade
Retail trade
47 establishments
- Construction
Construction
43 establishments
- Health care and social assistance
Health care and social assistance
37 establishments
- Other services (except public administration)
Other services (except public administration)
36 establishments
- Transportation and warehousing
Transportation and warehousing
29 establishments
What this shows Establishment counts come from the Census ZIP Code Business Patterns program, which counts physical business locations rather than employees or revenue.
Source: U.S. Census Bureau, American Community Survey 5-Year Estimates + ZIP Code Business Patterns + FHFA HPI ACS demographics and median rent, ZBP business establishments, FHFA HPI for ZIP 46221, Indianapolis, IN · 2023 Census ACS 5-Year Estimates use a rolling 60-month sample for stable small-geography estimates; ZBP updated annually; FHFA HPI updated quarterly/annually.
Quick Facts
26,393
Population
51.6
Area (sq mi)
511
People / sq mi
Indiana/Indianapolis
Time Zone
standard
ZIP Type
Who lives in ZIP 46221?
34.5
Median Age
50.1%
Male
49.9%
Female
10.6%
Foreign-Born
Hispanic or Latino is an ethnicity category from the Census Bureau and may overlap with other categories above.
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
How much do residents earn?
$65,280
Median Household Income
-11% vs state
$29,663
Per Capita Income
18.4%
Poverty Rate
6.1%
Unemployment Rate
27.1 min
Mean Commute Time
How ZIP 46221 ranks nationally
Indianapolis, IN household income vs. every US ZIP code
Median household income, the full national distribution, with this ZIP marked
$65,280 39th percentile higher than 39% of 30,318 US ZIPs
Each bar is a $20K-wide band; taller bars hold more US ZIPs. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.
Source U.S. Census Bureau, ACS 5-Year Estimates · 2019–2023
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
What is the education profile here?
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
What does housing look like?
11,140
Total Housing Units
10,117
Occupied Units
1,023
Vacant Units
2.66
Avg Household Size
Occupancy Type
$191,300
Median Home Value
-1% vs state
$1,137
Median Rent
1976
Median Year Built
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
How have home values changed over time?
FHFA House Price Index, annual appreciation data based on repeat sales and appraisals
+9.1%
YoY Change (2024)
219
HPI Index (2000 = 100)
+119%
Total Change Since 2000
Home values in ZIP 46221 have increased 9.1% over the past year (2024). Since 2000, this ZIP has seen +119% cumulative appreciation.
| Year | Annual Change | HPI Index |
|---|---|---|
| 2020 | +5.6% | 139 |
| 2021 | +15.5% | 160 |
| 2022 | +14.1% | 183 |
| 2023 | +9.7% | 201 |
| 2024 | +9.1% | 219 |
Source: Federal Housing Finance Agency (FHFA) House Price Index, All-Transactions, Five-Digit ZIP Codes (Developmental Index). Index base = 100 in year 2000. Data through 2024. ZIP codes with few transactions may show missing values.
What businesses operate in this ZIP?
Census Bureau data shows 341 business establishments in ZIP 46221, employing approximately 10,775 people with a combined annual payroll of $1,263,921,000.
341
Businesses
10,775
Employees
$1.3B
Annual Payroll
15
Industry Sectors
| Industry | Establishments | % of Total |
|---|---|---|
| Retail trade | 47 | 13.8% |
| Construction | 43 | 12.6% |
| Health care and social assistance | 37 | 10.8% |
| Other services (except public administration) | 36 | 10.6% |
| Transportation and warehousing | 29 | 8.5% |
| Accommodation and food services | 29 | 8.5% |
| Wholesale trade | 27 | 7.9% |
| Administrative and support and waste management and remediation services | 26 | 7.6% |
| Real estate and rental and leasing | 21 | 6.2% |
| Manufacturing | 12 | 3.5% |
| Information | 9 | 2.6% |
| Professional, scientific, and technical services | 9 | 2.6% |
| Finance and insurance | 6 | 1.8% |
| Utilities | 3 | 0.9% |
| Management of companies and enterprises | 3 | 0.9% |
Source: U.S. Census Bureau, ZIP Code Business Patterns (ZBP), 2023. Employment figures may include noise for disclosure avoidance.
Nearby ZIP Codes
Want a side-by-side? Compare 46221 vs 46241 →
ZIP 46221 vs its nearest neighbors, by population
Resident population of this ZIP and the closest reporting ZIP codes within ~10 miles.
- 46227
Indianapolis (46227)
57,086 residents
- 46224
Indianapolis (46224)
35,094 residents
- 46222
Indianapolis (46222)
34,044 residents
- 46241
Indianapolis (46241)
30,670 residents
- 46142
Greenwood (46142)
30,413 residents
- 46217
Indianapolis (46217)
29,358 residents
- 46221
Indianapolis (46221)
26,393 residents
- 46113 14,063
Camby (46113)
14,063 residents
- 46231 10,440
Indianapolis (46231)
10,440 residents
What this shows Among its immediate neighbors, ZIP 46221 ranks #7 by population - useful context the national average alone can't give.
ZIP 46221 vs its nearest neighbors, by median income
Median household income of this ZIP and the closest reporting ZIP codes within ~10 miles.
- 46217
Indianapolis (46217)
$92,029 median income
- 46142
Greenwood (46142)
$89,001 median income
- 46113
Camby (46113)
$84,463 median income
- 46231
Indianapolis (46231)
$71,825 median income
- 46221
Indianapolis (46221)
$65,280 median income
- 46224
Indianapolis (46224)
$55,986 median income
- 46225
Indianapolis (46225)
$55,190 median income
- 46241
Indianapolis (46241)
$53,653 median income
- 46227
Indianapolis (46227)
$53,629 median income
What this shows By household income, ZIP 46221 ranks #5 of 9 neighboring ZIPs, local affluence varies block to block, not just metro to metro.
| ZIP Code | City | Population | Distance |
|---|---|---|---|
| 46241 | Indianapolis, IN | 30,670 | 2.8 mi |
| 46217 | Indianapolis, IN | 29,358 | 2.7 mi |
| 46183 | West Newton, IN | 82 | 3.6 mi |
| 46231 | Indianapolis, IN | 10,440 | 4.8 mi |
| 46222 | Indianapolis, IN | 34,044 | 7.0 mi |
| 46224 | Indianapolis, IN | 35,094 | 7.2 mi |
| 46227 | Indianapolis, IN | 57,086 | 5.8 mi |
| 46225 | Indianapolis, IN | 7,319 | 5.2 mi |
| 46113 | Camby, IN | 14,063 | 5.4 mi |
| 46142 | Greenwood, IN | 30,413 | 5.9 mi |
More ZIP Codes in Marion County
Related Areas
Frequently Asked Questions
What county is ZIP code 46221 in? ▼
What is the population of ZIP code 46221? ▼
What is the median household income in ZIP 46221? ▼
What is the average home value in ZIP 46221? ▼
What is the demographic makeup of ZIP 46221? ▼
How many businesses are in ZIP code 46221? ▼
What are the main industries in ZIP code 46221? ▼
How have home values changed in ZIP code 46221? ▼
What is the education level in ZIP code 46221? ▼
What is the average commute time in ZIP 46221? ▼
What percentage of residents own vs. rent in ZIP 46221? ▼
What is the poverty rate in ZIP code 46221? ▼
Read our methodology to see how this data is sourced, computed, and verified.