ZIP Code 46221
standardSource:
Indianapolis · Marion County · Indiana
- Population
- 26,393
- Median income
- $65,280
- Median home value
- $191,300
- Bachelor's or higher
- 16.0%
- Land area
- 51.6 sq mi
511/sq mi
▼ 14% vs US
higher than 39% of US ZIPs
▼ 31% vs US
higher than 41% of US ZIPs
Median age 34.5
Indiana/Indianapolis
ZIP code 46221 in Indianapolis, Indiana has a population of 26,393. The median household income is $65,280, which is 14% below the national average. Median home value is $191,300, 31% below the US average. 16.0% of residents hold a bachelor's degree or higher.
ZIP code 46221 is classified by USPS as a standard delivery area and covers roughly 51.6 square miles in Indianapolis, Marion County, Indiana. The area is home to 26,393 residents, producing a population density of 511 people per square mile, and falls within the Indiana/Indianapolis time zone. These USPS and Census boundary values drive every downstream statistic on this page, including the benchmarks that compare 46221 against Indiana and the nation.
On the economic side, the median household income for ZIP 46221 sits at $65,280 (11% below the Indiana average), while per-capita income is $29,663. The poverty rate stands at 18.4% and the unemployment rate at 6.1%. On housing, the median home value is $191,300 (1% below the state average) with median rent at $1,137 per month, and 61.8% of occupied units are owner-occupied, a direct signal of whether 46221 behaves more like a homeowner neighborhood or a renter-heavy ZIP.
Education and household profile round out the picture: 16.0% of adults hold a bachelor's degree or higher, the median age is 34.5, and the average commute is 27 minutes. We also surface 10 nearby ZIP codes within roughly 10 miles and 6 additional ZIPs sharing Marion County, so you can benchmark 46221 against its immediate geography rather than a national average alone. Every figure is sourced from the U.S. Census Bureau American Community Survey 5-Year Estimates, HUD Fair Market Rents, and FHFA Home Price Index data, no estimates, no proprietary scoring. Verify with HUD →
Top industries in ZIP 46221
Top 5 sectors by establishment count
Which industries have the most business establishments in ZIP 46221.
- Retail trade
Retail trade
47 establishments
- Construction
Construction
43 establishments
- Health care and social assistance
Health care and social assistance
37 establishments
- Other services (except public administration)
Other services (except public administration)
36 establishments
- Transportation and warehousing
Transportation and warehousing
29 establishments
What this shows Establishment counts come from the Census ZIP Code Business Patterns program, which counts physical business locations rather than employees or revenue.
Source: U.S. Census Bureau, American Community Survey 5-Year Estimates + ZIP Code Business Patterns + HUD FMR + FHFA HPI ACS demographics, ZBP business establishments, HUD Fair Market Rents, FHFA HPI for ZIP 46221, Indianapolis, IN · 2023 Census ACS 5-Year Estimates use a rolling 60-month sample for stable small-geography estimates; ZBP updated annually; HUD FMR + FHFA HPI updated quarterly/annually.
Quick Facts
26,393
Population
51.6
Area (sq mi)
511
People / sq mi
Indiana/Indianapolis
Time Zone
standard
ZIP Type
Who lives in ZIP 46221?
34.5
Median Age
50.1%
Male
49.9%
Female
10.6%
Foreign-Born
Hispanic or Latino is an ethnicity category from the Census Bureau and may overlap with other categories above.
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
How much do residents earn?
$65,280
Median Household Income
-11% vs state
$29,663
Per Capita Income
18.4%
Poverty Rate
6.1%
Unemployment Rate
27.1 min
Mean Commute Time
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
What is the education profile here?
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
What does housing look like?
11,140
Total Housing Units
10,117
Occupied Units
1,023
Vacant Units
2.66
Avg Household Size
Occupancy Type
$191,300
Median Home Value
-1% vs state
$1,137
Median Rent
1976
Median Year Built
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
How have home values changed over time?
FHFA House Price Index, annual appreciation data based on repeat sales and appraisals
+9.1%
YoY Change (2024)
219
HPI Index (2000 = 100)
+119%
Total Change Since 2000
Home values in ZIP 46221 have increased 9.1% over the past year (2024). Since 2000, this ZIP has seen +119% cumulative appreciation.
| Year | Annual Change | HPI Index |
|---|---|---|
| 2020 | +5.6% | 139 |
| 2021 | +15.5% | 160 |
| 2022 | +14.1% | 183 |
| 2023 | +9.7% | 201 |
| 2024 | +9.1% | 219 |
Source: Federal Housing Finance Agency (FHFA) House Price Index, All-Transactions, Five-Digit ZIP Codes (Developmental Index). Index base = 100 in year 2000. Data through 2024. ZIP codes with few transactions may show missing values.
What businesses operate in this ZIP?
Census Bureau data shows 341 business establishments in ZIP 46221, employing approximately 10,775 people with a combined annual payroll of $1,263,921,000.
341
Businesses
10,775
Employees
$1.3B
Annual Payroll
15
Industry Sectors
| Industry | Establishments | % of Total |
|---|---|---|
| Retail trade | 47 | 13.8% |
| Construction | 43 | 12.6% |
| Health care and social assistance | 37 | 10.8% |
| Other services (except public administration) | 36 | 10.6% |
| Transportation and warehousing | 29 | 8.5% |
| Accommodation and food services | 29 | 8.5% |
| Wholesale trade | 27 | 7.9% |
| Administrative and support and waste management and remediation services | 26 | 7.6% |
| Real estate and rental and leasing | 21 | 6.2% |
| Manufacturing | 12 | 3.5% |
| Information | 9 | 2.6% |
| Professional, scientific, and technical services | 9 | 2.6% |
| Finance and insurance | 6 | 1.8% |
| Utilities | 3 | 0.9% |
| Management of companies and enterprises | 3 | 0.9% |
Source: U.S. Census Bureau, ZIP Code Business Patterns (ZBP), 2023. Employment figures may include noise for disclosure avoidance.
Nearby ZIP Codes
Want a side-by-side? Compare 46221 vs 46241 →
| ZIP Code | City | Population | Distance |
|---|---|---|---|
| 46241 | Indianapolis, IN | 30,670 | 2.8 mi |
| 46217 | Indianapolis, IN | 29,358 | 2.7 mi |
| 46183 | West Newton, IN | 82 | 3.6 mi |
| 46231 | Indianapolis, IN | 10,440 | 4.8 mi |
| 46222 | Indianapolis, IN | 34,044 | 7.0 mi |
| 46224 | Indianapolis, IN | 35,094 | 7.2 mi |
| 46227 | Indianapolis, IN | 57,086 | 5.8 mi |
| 46225 | Indianapolis, IN | 7,319 | 5.2 mi |
| 46113 | Camby, IN | 14,063 | 5.4 mi |
| 46142 | Greenwood, IN | 30,413 | 5.9 mi |
More ZIP Codes in Marion County
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Frequently Asked Questions
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What is the population of ZIP code 46221? ▼
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How many businesses are in ZIP code 46221? ▼
What are the main industries in ZIP code 46221? ▼
How have home values changed in ZIP code 46221? ▼
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What percentage of residents own vs. rent in ZIP 46221? ▼
What is the poverty rate in ZIP code 46221? ▼
ZIP Code Research Guides
Official Data Resources for Indianapolis, IN
Verify and explore additional data for this area using these official government sources.
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023). Business data: Source: Census ZIP Code Business Patterns (ZBP) 2023. Home value trends: Source: FHFA House Price Index (HPI), Five-Digit ZIP Codes.
PlainZIP is not affiliated with the U.S. Census Bureau or any government agency.
Read our methodology , how this data is sourced, computed, and verified.