Milwaukee, WI · standard
ZIP Code 53221
Milwaukee County, Wisconsin — Census ACS demographics, housing tenure, and business patterns, benchmarked against every US ZIP.
- 37,701
- 1,594/sq mi
- $63,265
- Median income
- $219,600
- Median home value
- 24.7%
- Bachelor's or higher
The verdict
Milwaukee pairs a below-median household income with below-median home values, in a low-density, mixed-tenure area.
- 35th pct
- household income, US ZIPs
- 49th pct
- home value, US ZIPs
- 1,594
- people per sq mi
- 57%
- owner-occupied homes
Source: U.S. Census Bureau ACS 5-Year Estimates (2019–2023). Percentiles rank ZIP 53221 against every reporting US ZIP.
ZIP code 53221 is classified by USPS as a standard delivery area and covers roughly 23.6 square miles in Milwaukee, Milwaukee County, Wisconsin. The area is home to 37,701 residents, producing a population density of 1,594 people per square mile, and falls within the Chicago time zone. These USPS and Census boundary values drive every downstream statistic on this page, including the benchmarks that compare 53221 against Wisconsin and the nation.
On the economic side, the median household income for ZIP 53221 sits at $63,265 (19% below the Wisconsin average), while per-capita income is $35,103. The poverty rate stands at 14.6% and the unemployment rate at 3.7%. On housing, the median home value is $219,600 (12% below the state average) with median rent at $1,119 per month, and 56.9% of occupied units are owner-occupied, a direct signal of whether 53221 behaves more like a homeowner neighborhood or a renter-heavy ZIP.
Education and household profile round out the picture: 24.7% of adults hold a bachelor's degree or higher, the median age is 38.8, and the average commute is 24 minutes. We also surface 10 nearby ZIP codes within roughly 10 miles and 6 additional ZIPs sharing Milwaukee County, so you can benchmark 53221 against its immediate geography rather than a national average alone. Every figure is sourced from the U.S. Census Bureau American Community Survey 5-Year Estimates, HUD Fair Market Rents, and FHFA Home Price Index data, no estimates, no proprietary scoring. Verify with HUD →
Top industries in ZIP 53221
Top 5 sectors by establishment count
Which industries have the most business establishments in ZIP 53221.
- Retail trade
Retail trade
116 establishments
- Health care and social assistance
Health care and social assistance
95 establishments
- Accommodation and food services
Accommodation and food services
83 establishments
- Other services (except public administration)
Other services (except public administration)
60 establishments
- Transportation and warehousing
Transportation and warehousing
54 establishments
What this shows Establishment counts come from the Census ZIP Code Business Patterns program, which counts physical business locations rather than employees or revenue.
Source: U.S. Census Bureau, American Community Survey 5-Year Estimates + ZIP Code Business Patterns + HUD FMR + FHFA HPI ACS demographics, ZBP business establishments, HUD Fair Market Rents, FHFA HPI for ZIP 53221, Milwaukee, WI · 2023 Census ACS 5-Year Estimates use a rolling 60-month sample for stable small-geography estimates; ZBP updated annually; HUD FMR + FHFA HPI updated quarterly/annually.
Quick Facts
37,701
Population
23.6
Area (sq mi)
1,594
People / sq mi
Chicago
Time Zone
standard
ZIP Type
Who lives in ZIP 53221?
38.8
Median Age
47.3%
Male
52.7%
Female
17.6%
Foreign-Born
Hispanic or Latino is an ethnicity category from the Census Bureau and may overlap with other categories above.
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
How much do residents earn?
$63,265
Median Household Income
-19% vs state
$35,103
Per Capita Income
14.6%
Poverty Rate
3.7%
Unemployment Rate
24.1 min
Mean Commute Time
How ZIP 53221 ranks nationally
Household income vs. every US ZIP code
Median household income — the full national distribution, with this ZIP marked
$63,265 35th percentile higher than 35% of 30,318 US ZIPs
Each bar is a $20K-wide band; taller bars hold more US ZIPs. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.
Source U.S. Census Bureau — ACS 5-Year Estimates · 2019–2023
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
What is the education profile here?
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
What does housing look like?
16,865
Total Housing Units
16,293
Occupied Units
572
Vacant Units
2.32
Avg Household Size
Occupancy Type
$219,600
Median Home Value
-12% vs state
$1,119
Median Rent
1967
Median Year Built
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
How have home values changed over time?
FHFA House Price Index, annual appreciation data based on repeat sales and appraisals
+6.0%
YoY Change (2024)
223
HPI Index (2000 = 100)
+123%
Total Change Since 2000
Home values in ZIP 53221 have increased 6.0% over the past year (2024). Since 2000, this ZIP has seen +123% cumulative appreciation.
| Year | Annual Change | HPI Index |
|---|---|---|
| 2020 | +4.9% | 151 |
| 2021 | +11.0% | 168 |
| 2022 | +12.3% | 188 |
| 2023 | +11.6% | 210 |
| 2024 | +6.0% | 223 |
Source: Federal Housing Finance Agency (FHFA) House Price Index, All-Transactions, Five-Digit ZIP Codes (Developmental Index). Index base = 100 in year 2000. Data through 2024. ZIP codes with few transactions may show missing values.
What businesses operate in this ZIP?
Census Bureau data shows 635 business establishments in ZIP 53221, employing approximately 10,083 people with a combined annual payroll of $506,590,000.
635
Businesses
10,083
Employees
$506.6M
Annual Payroll
16
Industry Sectors
| Industry | Establishments | % of Total |
|---|---|---|
| Retail trade | 116 | 18.3% |
| Health care and social assistance | 95 | 15.0% |
| Accommodation and food services | 83 | 13.1% |
| Other services (except public administration) | 60 | 9.4% |
| Transportation and warehousing | 54 | 8.5% |
| Construction | 52 | 8.2% |
| Administrative and support and waste management and remediation services | 39 | 6.1% |
| Finance and insurance | 26 | 4.1% |
| Real estate and rental and leasing | 26 | 4.1% |
| Professional, scientific, and technical services | 22 | 3.5% |
| Manufacturing | 20 | 3.1% |
| Wholesale trade | 19 | 3.0% |
| Information | 8 | 1.3% |
| Educational services | 6 | 0.9% |
| Arts, entertainment, and recreation | 5 | 0.8% |
| Management of companies and enterprises | 3 | 0.5% |
Source: U.S. Census Bureau, ZIP Code Business Patterns (ZBP), 2023. Employment figures may include noise for disclosure avoidance.
Nearby ZIP Codes
Want a side-by-side? Compare 53221 vs 53215 →
ZIP 53221 vs its nearest neighbors, by population
Resident population of this ZIP and the closest reporting ZIP codes within ~10 miles.
- 53215
Milwaukee (53215)
60,953 residents
- 53204
Milwaukee (53204)
42,355 residents
- 53221
Milwaukee (53221)
37,701 residents
- 53207
Milwaukee (53207)
35,149 residents
- 53219
Milwaukee (53219)
33,880 residents
- 53220
Milwaukee (53220)
26,303 residents
- 53110 18,320
Cudahy (53110)
18,320 residents
- 53233 16,453
Milwaukee (53233)
16,453 residents
- 53129 13,973
Greendale (53129)
13,973 residents
What this shows Among its immediate neighbors, ZIP 53221 ranks #3 by population — useful context the national average alone can't give.
ZIP 53221 vs its nearest neighbors, by median income
Median household income of this ZIP and the closest reporting ZIP codes within ~10 miles.
- 53129
Greendale (53129)
$95,012 median income
- 53207
Milwaukee (53207)
$79,117 median income
- 53219
Milwaukee (53219)
$70,388 median income
- 53220
Milwaukee (53220)
$69,319 median income
- 53110
Cudahy (53110)
$66,719 median income
- 53221
Milwaukee (53221)
$63,265 median income
- 53235
Saint Francis (53235)
$57,368 median income
- 53215
Milwaukee (53215)
$54,289 median income
- 53204
Milwaukee (53204)
$45,934 median income
What this shows By household income, ZIP 53221 ranks #6 of 9 neighboring ZIPs — local affluence varies block to block, not just metro to metro.
| ZIP Code | City | Population | Distance |
|---|---|---|---|
| 53215 | Milwaukee, WI | 60,953 | 3.1 mi |
| 53220 | Milwaukee, WI | 26,303 | 2.5 mi |
| 53207 | Milwaukee, WI | 35,149 | 2.5 mi |
| 53129 | Greendale, WI | 13,973 | 3.0 mi |
| 53204 | Milwaukee, WI | 42,355 | 4.5 mi |
| 53110 | Cudahy, WI | 18,320 | 4.1 mi |
| 53235 | Saint Francis, WI | 9,270 | 3.8 mi |
| 53219 | Milwaukee, WI | 33,880 | 3.8 mi |
| 53233 | Milwaukee, WI | 16,453 | 5.7 mi |
| 53295 | Milwaukee, WI | 359 | 5.0 mi |
More ZIP Codes in Milwaukee County
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Frequently Asked Questions
What county is ZIP code 53221 in? ▼
What is the population of ZIP code 53221? ▼
What is the median household income in ZIP 53221? ▼
What is the average home value in ZIP 53221? ▼
What is the demographic makeup of ZIP 53221? ▼
How many businesses are in ZIP code 53221? ▼
What are the main industries in ZIP code 53221? ▼
How have home values changed in ZIP code 53221? ▼
What is the education level in ZIP code 53221? ▼
What is the average commute time in ZIP 53221? ▼
What percentage of residents own vs. rent in ZIP 53221? ▼
What is the poverty rate in ZIP code 53221? ▼
ZIP Code Research Guides
Official Data Resources for Milwaukee, WI
Verify and explore additional data for this area using these official government sources.
Read our methodology to see how this data is sourced, computed, and verified.