PlainZIP

Chillicothe, OH · standard

ZIP Code 45601

Ross County, Ohio - Census ACS demographics, housing tenure, and business patterns, benchmarked against every US ZIP.

57,842
65/sq mi
$59,748
Median income
$173,100
Median home value
18.1%
Bachelor's or higher

The verdict

Chillicothe pairs a below-median household income with below-median home values, in a rural, homeowner-dominated and unusually populous area.

29th pct
household income, US ZIPs
36th pct
home value, US ZIPs
65
people per sq mi
68%
owner-occupied homes

Source: U.S. Census Bureau ACS 5-Year Estimates (2019–2023). Percentiles rank ZIP 45601 against every reporting US ZIP.

ZIP code 45601 is a densely settled ZIP (a standard USPS delivery area) in Chillicothe, Ross County, Ohio, with 57,842 residents across 885.8 square miles, a density of 65 people per square mile, in the New York time zone.

ZIP 45601 reports a modest median household income of $59,748 (18% below the Ohio average), while per-capita income is $32,494. Local economic indicators show a 17.0% poverty rate alongside 4.0% unemployment. The typical home here is valued at $173,100 (12% below the state average); renters pay a median of $915 monthly, and 67.8% of units are owner-occupied.

Educational attainment sits below the national norm: 18.1% of adults hold a bachelor's degree or higher, the median age is 41.5, and the average commute is 24 minutes. A geography-based comparison follows: 2 ZIP codes within about 10 miles of 45601, plus 6 more within Ross County, give a clearer read than the national average alone.

Every figure on this page is sourced from the U.S. Census Bureau American Community Survey 5-Year Estimates (including median rent) and the FHFA House Price Index, no estimates, no proprietary scoring. Verify with Census →

Top industries in ZIP 45601

Top 5 sectors by establishment count in Chillicothe, OH

Which industries have the most business establishments in ZIP 45601.

establishments

What this shows Establishment counts come from the Census ZIP Code Business Patterns program, which counts physical business locations rather than employees or revenue.

Source U.S. Census Bureau · ZIP Code Business Patterns (ZBP) As of 2023

Source: U.S. Census Bureau, American Community Survey 5-Year Estimates + ZIP Code Business Patterns + FHFA HPI ACS demographics and median rent, ZBP business establishments, FHFA HPI for ZIP 45601, Chillicothe, OH · 2023 Census ACS 5-Year Estimates use a rolling 60-month sample for stable small-geography estimates; ZBP updated annually; FHFA HPI updated quarterly/annually.

Quick Facts

57,842

Population

885.8

Area (sq mi)

65

People / sq mi

New York

Time Zone

standard

ZIP Type

Neighborhood Scorecard
Get an A-F grade across income, safety, housing, rent, education, commute, and childcare for this ZIP code.
View Scorecard →

Who lives in ZIP 45601?

41.5

Median Age

52.9%

Male

47.1%

Female

1.2%

Foreign-Born

White 86.0%
African American 7.4%
Asian 0.6%
American Indian or Alaska Native 0.2%
Native Hawaiian or Pacific Islander 0.0%
Two or More Ethnicities 4.8%
Hispanic or Latino 1.7%

Hispanic or Latino is an ethnicity category from the Census Bureau and may overlap with other categories above.

Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)

How much do residents earn?

$59,748

Median Household Income

-18% vs state

$32,494

Per Capita Income

17.0%

Poverty Rate

4.0%

Unemployment Rate

24.2 min

Mean Commute Time

How ZIP 45601 ranks nationally

Chillicothe, OH household income vs. every US ZIP code

Median household income, the full national distribution, with this ZIP marked

$59,748 29th percentile higher than 29% of 30,318 US ZIPs

$0–$20,000: 118 US ZIPs (0%). Below this entry. $20,000–$40,000: 1,573 US ZIPs (5%). Below this entry. $40,000–$60,000: 7,092 US ZIPs (23%). This entry sits in this band. $60,000–$80,000: 9,980 US ZIPs (33%). Above this entry. $80,000–$100,000: 5,778 US ZIPs (19%). Above this entry. $100,000–$120,000: 2,855 US ZIPs (9%). Above this entry. $120,000–$140,000: 1,362 US ZIPs (4%). Above this entry. $140,000–$160,000: 686 US ZIPs (2%). Above this entry. $160,000–$180,000: 364 US ZIPs (1%). Above this entry. $180,000–$200,000: 186 US ZIPs (1%). Above this entry. $200,000–$220,000: 324 US ZIPs (1%). Above this entry. This ZIP $0 $200K+ every reporting US ZIP, bucketed by value

Each bar is a $20K-wide band; taller bars hold more US ZIPs. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source U.S. Census Bureau, ACS 5-Year Estimates · 2019–2023

Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)

What is the education profile here?

High School Graduate or Higher 60.4%
Bachelor's Degree or Higher 18.1%

Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)

What does housing look like?

23,192

Total Housing Units

21,678

Occupied Units

1,514

Vacant Units

2.34

Avg Household Size

Occupancy Type

Owner 67.8%
Renter 32.2%

$173,100

Median Home Value

-12% vs state

$915

Median Rent

1971

Median Year Built

Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)

How have home values changed over time?

FHFA House Price Index, annual appreciation data based on repeat sales and appraisals

+11.8%

YoY Change (2024)

205

HPI Index (2000 = 100)

+105%

Total Change Since 2000

Home values in ZIP 45601 have increased 11.8% over the past year (2024). Since 2000, this ZIP has seen +105% cumulative appreciation.

Year Annual Change HPI Index
2020 +6.1% 139
2021 +9.6% 153
2022 +15.1% 176
2023 +4.0% 183
2024 +11.8% 205

Source: Federal Housing Finance Agency (FHFA) House Price Index, All-Transactions, Five-Digit ZIP Codes (Developmental Index). Index base = 100 in year 2000. Data through 2024. ZIP codes with few transactions may show missing values.

What businesses operate in this ZIP?

Census Bureau data shows 1,070 business establishments in ZIP 45601, employing approximately 23,036 people with a combined annual payroll of $1,142,689,000.

1,070

Businesses

23,036

Employees

$1.1B

Annual Payroll

18

Industry Sectors

Industry Establishments % of Total
Retail trade 217 20.3%
Health care and social assistance 150 14.0%
Accommodation and food services 124 11.6%
Other services (except public administration) 120 11.2%
Construction 66 6.2%
Finance and insurance 61 5.7%
Professional, scientific, and technical services 58 5.4%
Administrative and support and waste management and remediation services 52 4.9%
Transportation and warehousing 46 4.3%
Real estate and rental and leasing 43 4.0%
Wholesale trade 40 3.7%
Manufacturing 31 2.9%
Arts, entertainment, and recreation 18 1.7%
Information 16 1.5%
Utilities 8 0.8%
Management of companies and enterprises 8 0.8%
Educational services 6 0.6%
Agriculture, forestry, fishing and hunting 4 0.4%

Source: U.S. Census Bureau, ZIP Code Business Patterns (ZBP), 2023. Employment figures may include noise for disclosure avoidance.

Nearby ZIP Codes

Want a side-by-side? Compare 45601 vs 45673 →

ZIP 45601 vs its nearest neighbors, by population

Resident population of this ZIP and the closest reporting ZIP codes within ~10 miles.

residents

What this shows Among its immediate neighbors, ZIP 45601 ranks the most populous - useful context the national average alone can't give.

Source U.S. Census Bureau · ACS 5-Year Estimates As of 2019–2023

ZIP 45601 vs its nearest neighbors, by median income

Median household income of this ZIP and the closest reporting ZIP codes within ~10 miles.

median income

What this shows By household income, ZIP 45601 ranks #3 of 3 neighboring ZIPs, local affluence varies block to block, not just metro to metro.

Source U.S. Census Bureau · ACS 5-Year Estimates As of 2019–2023
ZIP Code City Population Distance
45673 Richmond Dale, OH 385 10.6 mi
45644 Kingston, OH 4,249 11.6 mi

More ZIP Codes in Ross County

45612 standard
Bainbridge, OH
Pop: 5,303
45628 standard
Frankfort, OH
Pop: 5,211
45644 standard
Kingston, OH
Pop: 4,249
45647 standard
Londonderry, OH
Pop: 2,484
45681 standard
South Salem, OH
Pop: 1,689
43115 standard
Clarksburg, OH
Pop: 1,321

Related Areas

Ross County Chillicothe, OH Ohio

Frequently Asked Questions

What county is ZIP code 45601 in? ▼
ZIP code 45601 (Chillicothe) is located in Ross County, Ohio. Ross County contains multiple ZIP codes, see the full list at /counties/ross-oh.
What is the population of ZIP code 45601? ▼
ZIP code 45601 in Chillicothe, OH has a population of 57,842 according to the Census Bureau ACS 2023 estimates.
What is the median household income in ZIP 45601? ▼
The median household income in ZIP 45601 is $59,748, which is 22% below the national average of $76,288.
What is the average home value in ZIP 45601? ▼
The median home value in ZIP 45601 is $173,100, which is 38% below the national average of $278,155.
What is the demographic makeup of ZIP 45601? ▼
The largest racial group in ZIP 45601 is White at 86.0%. Hispanic or Latino residents make up 1.7% of the population.
How many businesses are in ZIP code 45601? ▼
ZIP code 45601 has 1,070 business establishments employing approximately 23,036 people, according to Census Bureau ZIP Code Business Patterns (ZBP) 2023 data.
What are the main industries in ZIP code 45601? ▼
The top industries by establishment count in ZIP 45601 are: Retail trade (217), Health care and social assistance (150), Accommodation and food services (124). There are 18 industry sectors represented in total.
How have home values changed in ZIP code 45601? ▼
According to the FHFA House Price Index, home values in ZIP 45601 increased by 11.8% in 2024. Since 2000, home values in this ZIP have appreciated by approximately 105%. This is a developmental index based on repeat sales and appraisal data from Fannie Mae and Freddie Mac.
What is the education level in ZIP code 45601? ▼
In ZIP code 45601, 60.4% of residents aged 25+ have a high school diploma or higher, and 18.1% hold a bachelor's degree or higher. These figures come from the Census Bureau ACS 5-Year Estimates (2023).
What is the average commute time in ZIP 45601? ▼
The mean commute time for workers in ZIP code 45601 is 24.2 minutes according to Census ACS data. The national average is roughly 26 minutes, so commuters here spend less time traveling to work than typical.
What percentage of residents own vs. rent in ZIP 45601? ▼
In ZIP code 45601, approximately 67.8% of occupied housing units are owner-occupied and 32.2% are renter-occupied, based on Census ACS 2023 data.
What is the poverty rate in ZIP code 45601? ▼
The poverty rate in ZIP code 45601 is 17.0% according to Census Bureau ACS 2023 estimates. This measures the percentage of the population living below the federal poverty threshold.

Read our methodology to see how this data is sourced, computed, and verified.