ZIP Code 45601
standardSource:
Chillicothe · Ross County · Ohio
- Population
- 57,842
- Median income
- $59,748
- Median home value
- $173,100
- Bachelor's or higher
- 18.1%
- Land area
- 885.8 sq mi
65/sq mi
▼ 22% vs US
higher than 29% of US ZIPs
▼ 38% vs US
higher than 36% of US ZIPs
Median age 41.5
New York
ZIP code 45601 in Chillicothe, Ohio has a population of 57,842. The median household income is $59,748, which is 22% below the national average. Median home value is $173,100, 38% below the US average. 18.1% of residents hold a bachelor's degree or higher.
ZIP code 45601 is classified by USPS as a standard delivery area and covers roughly 885.8 square miles in Chillicothe, Ross County, Ohio. The area is home to 57,842 residents, producing a population density of 65 people per square mile, and falls within the New York time zone. These USPS and Census boundary values drive every downstream statistic on this page, including the benchmarks that compare 45601 against Ohio and the nation.
On the economic side, the median household income for ZIP 45601 sits at $59,748 (18% below the Ohio average), while per-capita income is $32,494. The poverty rate stands at 17.0% and the unemployment rate at 4.0%. On housing, the median home value is $173,100 (12% below the state average) with median rent at $915 per month, and 67.8% of occupied units are owner-occupied, a direct signal of whether 45601 behaves more like a homeowner neighborhood or a renter-heavy ZIP.
Education and household profile round out the picture: 18.1% of adults hold a bachelor's degree or higher, the median age is 41.5, and the average commute is 24 minutes. We also surface 2 nearby ZIP codes within roughly 10 miles and 6 additional ZIPs sharing Ross County, so you can benchmark 45601 against its immediate geography rather than a national average alone. Every figure is sourced from the U.S. Census Bureau American Community Survey 5-Year Estimates, HUD Fair Market Rents, and FHFA Home Price Index data, no estimates, no proprietary scoring. Verify with HUD →
Top industries in ZIP 45601
Top 5 sectors by establishment count
Which industries have the most business establishments in ZIP 45601.
- Retail trade
Retail trade
217 establishments
- Health care and social assistance
Health care and social assistance
150 establishments
- Accommodation and food services
Accommodation and food services
124 establishments
- Other services (except public administration)
Other services (except public administration)
120 establishments
- Construction 66
Construction
66 establishments
What this shows Establishment counts come from the Census ZIP Code Business Patterns program, which counts physical business locations rather than employees or revenue.
Source: U.S. Census Bureau, American Community Survey 5-Year Estimates + ZIP Code Business Patterns + HUD FMR + FHFA HPI ACS demographics, ZBP business establishments, HUD Fair Market Rents, FHFA HPI for ZIP 45601, Chillicothe, OH · 2023 Census ACS 5-Year Estimates use a rolling 60-month sample for stable small-geography estimates; ZBP updated annually; HUD FMR + FHFA HPI updated quarterly/annually.
Quick Facts
57,842
Population
885.8
Area (sq mi)
65
People / sq mi
New York
Time Zone
standard
ZIP Type
Who lives in ZIP 45601?
41.5
Median Age
52.9%
Male
47.1%
Female
1.2%
Foreign-Born
Hispanic or Latino is an ethnicity category from the Census Bureau and may overlap with other categories above.
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
How much do residents earn?
$59,748
Median Household Income
-18% vs state
$32,494
Per Capita Income
17.0%
Poverty Rate
4.0%
Unemployment Rate
24.2 min
Mean Commute Time
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
What is the education profile here?
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
What does housing look like?
23,192
Total Housing Units
21,678
Occupied Units
1,514
Vacant Units
2.34
Avg Household Size
Occupancy Type
$173,100
Median Home Value
-12% vs state
$915
Median Rent
1971
Median Year Built
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
How have home values changed over time?
FHFA House Price Index, annual appreciation data based on repeat sales and appraisals
+11.8%
YoY Change (2024)
205
HPI Index (2000 = 100)
+105%
Total Change Since 2000
Home values in ZIP 45601 have increased 11.8% over the past year (2024). Since 2000, this ZIP has seen +105% cumulative appreciation.
| Year | Annual Change | HPI Index |
|---|---|---|
| 2020 | +6.1% | 139 |
| 2021 | +9.6% | 153 |
| 2022 | +15.1% | 176 |
| 2023 | +4.0% | 183 |
| 2024 | +11.8% | 205 |
Source: Federal Housing Finance Agency (FHFA) House Price Index, All-Transactions, Five-Digit ZIP Codes (Developmental Index). Index base = 100 in year 2000. Data through 2024. ZIP codes with few transactions may show missing values.
What businesses operate in this ZIP?
Census Bureau data shows 1,070 business establishments in ZIP 45601, employing approximately 23,036 people with a combined annual payroll of $1,142,689,000.
1,070
Businesses
23,036
Employees
$1.1B
Annual Payroll
18
Industry Sectors
| Industry | Establishments | % of Total |
|---|---|---|
| Retail trade | 217 | 20.3% |
| Health care and social assistance | 150 | 14.0% |
| Accommodation and food services | 124 | 11.6% |
| Other services (except public administration) | 120 | 11.2% |
| Construction | 66 | 6.2% |
| Finance and insurance | 61 | 5.7% |
| Professional, scientific, and technical services | 58 | 5.4% |
| Administrative and support and waste management and remediation services | 52 | 4.9% |
| Transportation and warehousing | 46 | 4.3% |
| Real estate and rental and leasing | 43 | 4.0% |
| Wholesale trade | 40 | 3.7% |
| Manufacturing | 31 | 2.9% |
| Arts, entertainment, and recreation | 18 | 1.7% |
| Information | 16 | 1.5% |
| Utilities | 8 | 0.8% |
| Management of companies and enterprises | 8 | 0.8% |
| Educational services | 6 | 0.6% |
| Agriculture, forestry, fishing and hunting | 4 | 0.4% |
Source: U.S. Census Bureau, ZIP Code Business Patterns (ZBP), 2023. Employment figures may include noise for disclosure avoidance.
Nearby ZIP Codes
Want a side-by-side? Compare 45601 vs 45673 →
More ZIP Codes in Ross County
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Frequently Asked Questions
What county is ZIP code 45601 in? ▼
What is the population of ZIP code 45601? ▼
What is the median household income in ZIP 45601? ▼
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What is the demographic makeup of ZIP 45601? ▼
How many businesses are in ZIP code 45601? ▼
What are the main industries in ZIP code 45601? ▼
How have home values changed in ZIP code 45601? ▼
What is the education level in ZIP code 45601? ▼
What is the average commute time in ZIP 45601? ▼
What percentage of residents own vs. rent in ZIP 45601? ▼
What is the poverty rate in ZIP code 45601? ▼
ZIP Code Research Guides
Official Data Resources for Chillicothe, OH
Verify and explore additional data for this area using these official government sources.
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023). Business data: Source: Census ZIP Code Business Patterns (ZBP) 2023. Home value trends: Source: FHFA House Price Index (HPI), Five-Digit ZIP Codes.
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Read our methodology , how this data is sourced, computed, and verified.