Chillicothe, OH · standard
ZIP Code 45601
Ross County, Ohio - Census ACS demographics, housing tenure, and business patterns, benchmarked against every US ZIP.
- 57,842
- 65/sq mi Moderate-density area
- $59,748
- Median income Below-median income area
- $173,100
- Median home value Near-median home value
- 18.1%
- Bachelor's or higher Near-average bachelor's attainment
National ZIP placement
Chillicothe pairs a below-median household income with below-median home values, in a rural, homeowner-dominated and unusually populous area.
- 29th pct
- household income, US ZIPs
- 36th pct
- home value, US ZIPs
- 65
- people per sq mi
- 68%
- owner-occupied homes
Source: U.S. Census Bureau ACS 5-Year Estimates (2019–2023). Percentiles rank ZIP 45601 against every reporting US ZIP.
FHFA HPI release change
What changed in the latest House Price Index year
- FHFA House Price Index values in ZIP 45601 (Chillicothe, OH) rose +11.8% from 2023 to 2024. The all-transactions index moved from 183.0 in 2023 to 204.5 in 2024 (2000 = 100).
ZIP code 45601 is a densely settled ZIP (a standard USPS delivery area) in Chillicothe, Ross County, Ohio, with 57,842 residents across 885.8 square miles, a density of 65 people per square mile, in the New York time zone.
ZIP 45601 reports a modest median household income of $59,748 (18% below the average Ohio ZIP), while per-capita income is $32,494. The poverty rate is 17.0%, with unemployment at 4.0%; those measures add context to the income figure. Median home value is $173,100 (12% below the average Ohio ZIP) and median rent is $915; 67.8% of occupied homes are owner-occupied.
Educational attainment sits below the national norm: 18.1% of adults hold a bachelor's degree or higher, the median age is 41.5, and the average commute is 24 minutes. The page also surfaces 2 ZIP codes within roughly 10 miles and 6 more in Ross County, so 45601 can be compared with both its immediate and county-level context.
Every figure on this page is sourced from the U.S. Census Bureau American Community Survey 5-Year Estimates (including median rent) and the FHFA House Price Index, no estimates, no proprietary scoring. Verify with Census →
Top industries in ZIP 45601
Top 5 sectors by establishment count in Chillicothe, OH
Which industries have the most business establishments in ZIP 45601.
- Retail trade
Retail trade
217 establishments
- Health care and social assistance
Health care and social assistance
150 establishments
- Accommodation and food services
Accommodation and food services
124 establishments
- Other services (except public administration)
Other services (except public administration)
120 establishments
- Construction 66
Construction
66 establishments
What this shows Establishment counts come from the Census ZIP Code Business Patterns program, which counts physical business locations rather than employees or revenue.
Source: U.S. Census Bureau, American Community Survey 5-Year Estimates + ZIP Code Business Patterns + FHFA HPI ACS demographics and median rent, ZBP business establishments, FHFA HPI for ZIP 45601, Chillicothe, OH · 2023 Census ACS 5-Year Estimates use a rolling 60-month sample for stable small-geography estimates; ZBP updated annually; FHFA HPI updated quarterly/annually.
Quick Facts
57,842
Population
885.8
Area (sq mi)
65
People / sq mi
New York
Time Zone
standard
ZIP Type
Who lives in ZIP 45601?
41.5
Median Age
52.9%
Male
47.1%
Female
1.2%
Foreign-Born
Hispanic or Latino is an ethnicity category from the Census Bureau and may overlap with other categories above.
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
How much do residents earn?
$59,748
Median Household Income
-18% vs state ZIP avg
$32,494
Per Capita Income
17.0%
Poverty Rate
4.0%
Unemployment Rate
24.2 min
Mean Commute Time
How ZIP 45601 ranks nationally
Chillicothe, OH household income vs. every US ZIP code
Median household income, the full national distribution, with this ZIP marked
$59,748 29th percentile higher than 29% of 30,318 US ZIPs
Each bar is a $20K-wide band; taller bars hold more US ZIPs. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.
Source U.S. Census Bureau, ACS 5-Year Estimates · 2019–2023
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
What is the education profile here?
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
What does housing look like?
Housing stock: occupied vs vacant
23,192housing units
23,192
Total Housing Units
21,678
Occupied Units
1,514
Vacant Units
2.34
Avg Household Size
Occupancy Type
$173,100
Median Home Value
-12% vs state ZIP avg
$915
Median Rent
1971
Median Year Built
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
How have home values changed over time?
FHFA House Price Index, annual appreciation data based on repeat sales and appraisals
+11.8%
YoY Change (2024)
205
HPI Index (2000 = 100)
+105%
Total Change Since 2000
Home values in ZIP 45601 have increased 11.8% over the past year (2024). Since 2000, this ZIP has seen +105% cumulative appreciation.
| Year | Annual Change | HPI Index |
|---|---|---|
| 2020 | +6.1% | 139 |
| 2021 | +9.6% | 153 |
| 2022 | +15.1% | 176 |
| 2023 | +4.0% | 183 |
| 2024 | +11.8% | 205 |
Source: Federal Housing Finance Agency (FHFA) House Price Index, All-Transactions, Five-Digit ZIP Codes (Developmental Index). Index base = 100 in year 2000. Data through 2024. ZIP codes with few transactions may show missing values.
What businesses operate in this ZIP?
Census Bureau data shows 1,070 business establishments in ZIP 45601, employing approximately 23,036 people with a combined annual payroll of $1,142,689,000.
1,070
Businesses
23,036
Employees
$1.1B
Annual Payroll
18
Industry Sectors
| Industry | Establishments | % of Total |
|---|---|---|
| Retail trade | 217 | 20.3% |
| Health care and social assistance | 150 | 14.0% |
| Accommodation and food services | 124 | 11.6% |
| Other services (except public administration) | 120 | 11.2% |
| Construction | 66 | 6.2% |
| Finance and insurance | 61 | 5.7% |
| Professional, scientific, and technical services | 58 | 5.4% |
| Administrative and support and waste management and remediation services | 52 | 4.9% |
| Transportation and warehousing | 46 | 4.3% |
| Real estate and rental and leasing | 43 | 4.0% |
| Wholesale trade | 40 | 3.7% |
| Manufacturing | 31 | 2.9% |
| Arts, entertainment, and recreation | 18 | 1.7% |
| Information | 16 | 1.5% |
| Utilities | 8 | 0.8% |
| Management of companies and enterprises | 8 | 0.8% |
| Educational services | 6 | 0.6% |
| Agriculture, forestry, fishing and hunting | 4 | 0.4% |
Source: U.S. Census Bureau, ZIP Code Business Patterns (ZBP), 2023. Employment figures may include noise for disclosure avoidance.
Nearby ZIP Codes
Want a side-by-side? Compare 45601 vs 45673 →
ZIP 45601 vs its nearest neighbors, by population
Resident population of this ZIP and the closest reporting ZIP codes within ~10 miles.
- 45601
Chillicothe (45601)
57,842 residents
- 45644 4,249
Kingston (45644)
4,249 residents
- 45673 385
Richmond Dale (45673)
385 residents
What this shows Among its immediate neighbors, ZIP 45601 ranks the most populous - useful context the national average alone can't give.
ZIP 45601 vs its nearest neighbors, by median income
Median household income of this ZIP and the closest reporting ZIP codes within ~10 miles.
- 45644
Kingston (45644)
$74,219 median income
- 45673
Richmond Dale (45673)
$64,438 median income
- 45601
Chillicothe (45601)
$59,748 median income
What this shows By household income, ZIP 45601 ranks #3 of 3 neighboring ZIPs, local affluence varies block to block, not just metro to metro.
Nationwide ZIPs with similar ACS profiles
Two Census-derived peer sets for ZIP 45601, both outside OH so the neighborhoods are not geographic containment (Nearby and same-county blocks stay local).
Similar population
Nearest cross-state ZIPs by resident population (57,842 here; floor ≥1,000).
Similar median household income
Nearest cross-state ZIPs by ACS median household income.
More ZIP Codes in Ross County
Related Areas
Frequently Asked Questions
What county is ZIP code 45601 in?
ZIP code 45601 (Chillicothe) is located in Ross County, Ohio. Ross County contains multiple ZIP codes, see the full list at /counties/ross-oh.
What is the population of ZIP code 45601?
ZIP code 45601 in Chillicothe, OH has a population of 57,842 according to the Census Bureau ACS 2023 estimates.
What is the median household income in ZIP 45601?
The median household income in ZIP 45601 is $59,748, which is 22% below the national average of $76,288.
What is the average home value in ZIP 45601?
The median home value in ZIP 45601 is $173,100, which is 38% below the national average of $278,155.
What is the demographic makeup of ZIP 45601?
The largest racial group in ZIP 45601 is White at 86.0%. Hispanic or Latino residents make up 1.7% of the population.
How many businesses are in ZIP code 45601?
ZIP code 45601 has 1,070 business establishments employing approximately 23,036 people, according to Census Bureau ZIP Code Business Patterns (ZBP) 2023 data.
What are the main industries in ZIP code 45601?
The top industries by establishment count in ZIP 45601 are: Retail trade (217), Health care and social assistance (150), Accommodation and food services (124). There are 18 industry sectors represented in total.
How have home values changed in ZIP code 45601?
According to the FHFA House Price Index, home values in ZIP 45601 increased by 11.8% in 2024. Since 2000, home values in this ZIP have appreciated by approximately 105%. This is a developmental index based on repeat sales and appraisal data from Fannie Mae and Freddie Mac.
What is the education level in ZIP code 45601?
In ZIP code 45601, 60.4% of residents aged 25+ have a high school diploma or higher, and 18.1% hold a bachelor's degree or higher. These figures come from the Census Bureau ACS 5-Year Estimates (2023).
What is the average commute time in ZIP 45601?
The mean commute time for workers in ZIP code 45601 is 24.2 minutes according to Census ACS data. The national average is roughly 26 minutes, so commuters here spend less time traveling to work than typical.
What percentage of residents own vs. rent in ZIP 45601?
In ZIP code 45601, approximately 67.8% of occupied housing units are owner-occupied and 32.2% are renter-occupied, based on Census ACS 2023 data.
What is the poverty rate in ZIP code 45601?
The poverty rate in ZIP code 45601 is 17.0% according to Census Bureau ACS 2023 estimates. This measures the percentage of the population living below the federal poverty threshold.
Related
Take this with you
What to do with ZIP 45601's numbers, next.
- See how ZIP 45601 compares to a neighboring ZIP code on the same Census fields Compare this ZIP
- Check where Chillicothe, OH ranks among every U.S. ZIP code on income, education, or homeownership View national rankings
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ZIP Code Tabulation Areas (ZCTAs) are Census Bureau approximations of USPS ZIP codes; figures describe the ZCTA area, not any single address within it.