Adrian, MI · standard
ZIP Code 49221
Lenawee County, Michigan - Census ACS demographics, housing tenure, and business patterns, benchmarked against every US ZIP.
- 41,310
- 135/sq mi
- $65,977
- Median income
- $170,400
- Median home value
- 22.3%
- Bachelor's or higher
The verdict
Adrian pairs a below-median household income with below-median home values, in a rural, homeowner-dominated area.
- 40th pct
- household income, US ZIPs
- 34th pct
- home value, US ZIPs
- 135
- people per sq mi
- 71%
- owner-occupied homes
Source: U.S. Census Bureau ACS 5-Year Estimates (2019–2023). Percentiles rank ZIP 49221 against every reporting US ZIP.
ZIP code 49221 is a densely settled ZIP (a standard USPS delivery area) in Adrian, Lenawee County, Michigan, with 41,310 residents across 306.7 square miles, a density of 135 people per square mile, in the Detroit time zone.
ZIP 49221 reports a modest median household income of $65,977 (10% below the Michigan average), while per-capita income is $31,437. The poverty rate stands at 15.5% and the unemployment rate at 4.5%. On housing, the median home value is $170,400 (22% below the state average) with median rent at $992 per month, and 71.1% of occupied units are owner-occupied.
Educational attainment sits below the national norm: 22.3% of adults hold a bachelor's degree or higher, the median age is 41.1, and the average commute is 24 minutes. To put 49221 in local context, 7 ZIP codes within roughly 10 miles appear further down this page alongside 6 additional ZIPs in Lenawee County, for a geography-aware comparison.
Every figure on this page is sourced from the U.S. Census Bureau American Community Survey 5-Year Estimates (including median rent) and the FHFA House Price Index, no estimates, no proprietary scoring. Verify with Census →
Top industries in ZIP 49221
Top 5 sectors by establishment count in Adrian, MI
Which industries have the most business establishments in ZIP 49221.
- Retail trade
Retail trade
138 establishments
- Health care and social assistance
Health care and social assistance
134 establishments
- Other services (except public administration)
Other services (except public administration)
90 establishments
- Accommodation and food services
Accommodation and food services
86 establishments
- Construction
Construction
67 establishments
What this shows Establishment counts come from the Census ZIP Code Business Patterns program, which counts physical business locations rather than employees or revenue.
Source: U.S. Census Bureau, American Community Survey 5-Year Estimates + ZIP Code Business Patterns + FHFA HPI ACS demographics and median rent, ZBP business establishments, FHFA HPI for ZIP 49221, Adrian, MI · 2023 Census ACS 5-Year Estimates use a rolling 60-month sample for stable small-geography estimates; ZBP updated annually; FHFA HPI updated quarterly/annually.
Quick Facts
41,310
Population
306.7
Area (sq mi)
135
People / sq mi
Detroit
Time Zone
standard
ZIP Type
Who lives in ZIP 49221?
41.1
Median Age
51.9%
Male
48.1%
Female
2.7%
Foreign-Born
Hispanic or Latino is an ethnicity category from the Census Bureau and may overlap with other categories above.
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
How much do residents earn?
$65,977
Median Household Income
-10% vs state
$31,437
Per Capita Income
15.5%
Poverty Rate
4.5%
Unemployment Rate
23.7 min
Mean Commute Time
How ZIP 49221 ranks nationally
Adrian, MI household income vs. every US ZIP code
Median household income, the full national distribution, with this ZIP marked
$65,977 40th percentile higher than 40% of 30,318 US ZIPs
Each bar is a $20K-wide band; taller bars hold more US ZIPs. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.
Source U.S. Census Bureau, ACS 5-Year Estimates · 2019–2023
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
What is the education profile here?
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
What does housing look like?
17,187
Total Housing Units
15,658
Occupied Units
1,529
Vacant Units
2.34
Avg Household Size
Occupancy Type
$170,400
Median Home Value
-22% vs state
$992
Median Rent
1968
Median Year Built
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
How have home values changed over time?
FHFA House Price Index, annual appreciation data based on repeat sales and appraisals
+4.8%
YoY Change (2024)
164
HPI Index (2000 = 100)
+64%
Total Change Since 2000
Home values in ZIP 49221 have increased 4.8% over the past year (2024). Since 2000, this ZIP has seen +64% cumulative appreciation.
| Year | Annual Change | HPI Index |
|---|---|---|
| 2020 | +3.0% | 118 |
| 2021 | +13.6% | 134 |
| 2022 | +10.6% | 148 |
| 2023 | +6.1% | 157 |
| 2024 | +4.8% | 164 |
Source: Federal Housing Finance Agency (FHFA) House Price Index, All-Transactions, Five-Digit ZIP Codes (Developmental Index). Index base = 100 in year 2000. Data through 2024. ZIP codes with few transactions may show missing values.
What businesses operate in this ZIP?
Census Bureau data shows 819 business establishments in ZIP 49221, employing approximately 14,453 people with a combined annual payroll of $671,869,000.
819
Businesses
14,453
Employees
$671.9M
Annual Payroll
17
Industry Sectors
| Industry | Establishments | % of Total |
|---|---|---|
| Retail trade | 138 | 16.9% |
| Health care and social assistance | 134 | 16.4% |
| Other services (except public administration) | 90 | 11.0% |
| Accommodation and food services | 86 | 10.5% |
| Construction | 67 | 8.2% |
| Finance and insurance | 56 | 6.8% |
| Professional, scientific, and technical services | 48 | 5.9% |
| Administrative and support and waste management and remediation services | 45 | 5.5% |
| Real estate and rental and leasing | 38 | 4.6% |
| Manufacturing | 35 | 4.3% |
| Wholesale trade | 21 | 2.6% |
| Transportation and warehousing | 14 | 1.7% |
| Educational services | 14 | 1.7% |
| Arts, entertainment, and recreation | 11 | 1.3% |
| Information | 10 | 1.2% |
| Management of companies and enterprises | 5 | 0.6% |
| Utilities | 3 | 0.4% |
Source: U.S. Census Bureau, ZIP Code Business Patterns (ZBP), 2023. Employment figures may include noise for disclosure avoidance.
Nearby ZIP Codes
Want a side-by-side? Compare 49221 vs 49287 →
ZIP 49221 vs its nearest neighbors, by population
Resident population of this ZIP and the closest reporting ZIP codes within ~10 miles.
- 49221
Adrian (49221)
41,310 residents
- 49286 14,797
Tecumseh (49286)
14,797 residents
- 49265 4,958
Onsted (49265)
4,958 residents
- 49287 2,099
Tipton (49287)
2,099 residents
- 49268 1,059
Palmyra (49268)
1,059 residents
- 49248 899
Jasper (49248)
899 residents
- 49279 797
Sand Creek (49279)
797 residents
- 49289 167
Weston (49289)
167 residents
What this shows Among its immediate neighbors, ZIP 49221 ranks the most populous - useful context the national average alone can't give.
ZIP 49221 vs its nearest neighbors, by median income
Median household income of this ZIP and the closest reporting ZIP codes within ~10 miles.
- 49287
Tipton (49287)
$88,068 median income
- 49248
Jasper (49248)
$81,250 median income
- 49268
Palmyra (49268)
$80,833 median income
- 49265
Onsted (49265)
$77,931 median income
- 49286
Tecumseh (49286)
$72,429 median income
- 49279
Sand Creek (49279)
$71,364 median income
- 49221
Adrian (49221)
$65,977 median income
What this shows By household income, ZIP 49221 ranks #7 of 7 neighboring ZIPs, local affluence varies block to block, not just metro to metro.
More ZIP Codes in Lenawee County
Related Areas
Frequently Asked Questions
What county is ZIP code 49221 in? ▼
What is the population of ZIP code 49221? ▼
What is the median household income in ZIP 49221? ▼
What is the average home value in ZIP 49221? ▼
What is the demographic makeup of ZIP 49221? ▼
How many businesses are in ZIP code 49221? ▼
What are the main industries in ZIP code 49221? ▼
How have home values changed in ZIP code 49221? ▼
What is the education level in ZIP code 49221? ▼
What is the average commute time in ZIP 49221? ▼
What percentage of residents own vs. rent in ZIP 49221? ▼
What is the poverty rate in ZIP code 49221? ▼
Read our methodology to see how this data is sourced, computed, and verified.