Chillicothe, MO · standard
ZIP Code 64601
Livingston County, Missouri - Census ACS demographics, housing tenure, and business patterns, benchmarked against every US ZIP.
- 12,438
- 20/sq mi Moderate-density area
- $63,061
- Median income Near-median income area
- $153,900
- Median home value Below-median home value
- 18.4%
- Bachelor's or higher Near-average bachelor's attainment
National ZIP placement
Chillicothe pairs a below-median household income with below-median home values, in a rural, homeowner-dominated area.
- 35th pct
- household income, US ZIPs
- 27th pct
- home value, US ZIPs
- 20
- people per sq mi
- 71%
- owner-occupied homes
Source: U.S. Census Bureau ACS 5-Year Estimates (2019–2023). Percentiles rank ZIP 64601 against every reporting US ZIP.
FHFA HPI release change
What changed in the latest House Price Index year
- FHFA House Price Index values in ZIP 64601 (Chillicothe, MO) rose +6.6% from 2023 to 2024. The all-transactions index moved from 202.9 in 2023 to 216.3 in 2024 (2000 = 100).
ZIP code 64601 is a mid-sized community (a standard USPS delivery area) in Chillicothe, Livingston County, Missouri, home to 12,438 residents across 621.9 square miles, a density of 20 people per square mile, in the Chicago time zone.
ZIP 64601 reports a modest median household income of $63,061 (6% below the average Missouri ZIP), while per-capita income is $33,673. The poverty rate is 12.4%, with unemployment at 2.8%; those measures add context to the income figure. Home values sit below the statewide ZIP benchmark: the median is $153,900 (19% below the average Missouri ZIP), and median rent is $769; owner occupancy is 70.7%.
Educational attainment sits below the national norm: 18.4% of adults hold a bachelor's degree or higher, the median age is 40, and the average commute is 19 minutes. The page also surfaces 4 ZIP codes within roughly 10 miles and 6 more in Livingston County, so 64601 can be compared with both its immediate and county-level context.
Every figure on this page is sourced from the U.S. Census Bureau American Community Survey 5-Year Estimates (including median rent) and the FHFA House Price Index, no estimates, no proprietary scoring. Verify with Census →
Top industries in ZIP 64601
Top 5 sectors by establishment count in Chillicothe, MO
Which industries have the most business establishments in ZIP 64601.
- Retail trade
Retail trade
61 establishments
- Other services (except public administration)
Other services (except public administration)
44 establishments
- Health care and social assistance
Health care and social assistance
38 establishments
- Construction
Construction
37 establishments
- Finance and insurance
Finance and insurance
31 establishments
What this shows Establishment counts come from the Census ZIP Code Business Patterns program, which counts physical business locations rather than employees or revenue.
Source: U.S. Census Bureau, American Community Survey 5-Year Estimates + ZIP Code Business Patterns + FHFA HPI ACS demographics and median rent, ZBP business establishments, FHFA HPI for ZIP 64601, Chillicothe, MO · 2023 Census ACS 5-Year Estimates use a rolling 60-month sample for stable small-geography estimates; ZBP updated annually; FHFA HPI updated quarterly/annually.
Quick Facts
12,438
Population
621.9
Area (sq mi)
20
People / sq mi
Chicago
Time Zone
standard
ZIP Type
Who lives in ZIP 64601?
40.0
Median Age
44.3%
Male
55.7%
Female
0.8%
Foreign-Born
Hispanic or Latino is an ethnicity category from the Census Bureau and may overlap with other categories above.
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
How much do residents earn?
$63,061
Median Household Income
-6% vs state ZIP avg
$33,673
Per Capita Income
12.4%
Poverty Rate
2.8%
Unemployment Rate
19.3 min
Mean Commute Time
How ZIP 64601 ranks among Missouri ZIPs
Chillicothe, MO household income vs. every Missouri ZIP code
Median household income among 948 reporting Missouri ZIPs (this ZIP's population is too small for a reliable national-corpus placement)
$63,061 Top 47% higher than 53% of 948 Missouri ZIPs
Each bar is a $20K-wide band; taller bars hold more Missouri ZIPs. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.
Source U.S. Census Bureau, ACS 5-Year Estimates · 2019–2023
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
What is the education profile here?
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
What does housing look like?
Housing stock: occupied vs vacant
5,247housing units
5,247
Total Housing Units
4,683
Occupied Units
564
Vacant Units
2.31
Avg Household Size
Occupancy Type
$153,900
Median Home Value
-19% vs state ZIP avg
$769
Median Rent
1969
Median Year Built
Source: U.S. Census Bureau, ACS 5-Year Estimates (2023)
How have home values changed over time?
FHFA House Price Index, annual appreciation data based on repeat sales and appraisals
+6.6%
YoY Change (2024)
216
HPI Index (2000 = 100)
+116%
Total Change Since 2000
Home values in ZIP 64601 have increased 6.6% over the past year (2024). Since 2000, this ZIP has seen +116% cumulative appreciation.
| Year | Annual Change | HPI Index |
|---|---|---|
| 2020 | +8.0% | 145 |
| 2021 | +11.6% | 162 |
| 2022 | +20.8% | 196 |
| 2023 | +3.4% | 203 |
| 2024 | +6.6% | 216 |
Source: Federal Housing Finance Agency (FHFA) House Price Index, All-Transactions, Five-Digit ZIP Codes (Developmental Index). Index base = 100 in year 2000. Data through 2024. ZIP codes with few transactions may show missing values.
What businesses operate in this ZIP?
Census Bureau data shows 369 business establishments in ZIP 64601, employing approximately 5,009 people with a combined annual payroll of $216,830,000.
369
Businesses
5,009
Employees
$216.8M
Annual Payroll
14
Industry Sectors
| Industry | Establishments | % of Total |
|---|---|---|
| Retail trade | 61 | 16.5% |
| Other services (except public administration) | 44 | 11.9% |
| Health care and social assistance | 38 | 10.3% |
| Construction | 37 | 10.0% |
| Finance and insurance | 31 | 8.4% |
| Accommodation and food services | 31 | 8.4% |
| Professional, scientific, and technical services | 25 | 6.8% |
| Wholesale trade | 20 | 5.4% |
| Manufacturing | 19 | 5.2% |
| Transportation and warehousing | 17 | 4.6% |
| Administrative and support and waste management and remediation services | 13 | 3.5% |
| Information | 11 | 3.0% |
| Arts, entertainment, and recreation | 8 | 2.2% |
| Real estate and rental and leasing | 7 | 1.9% |
Source: U.S. Census Bureau, ZIP Code Business Patterns (ZBP), 2023. Employment figures may include noise for disclosure avoidance.
Nearby ZIP Codes
Want a side-by-side? Compare 64601 vs 64686 →
ZIP 64601 vs its nearest neighbors, by population
Resident population of this ZIP and the closest reporting ZIP codes within ~10 miles.
- 64601
Chillicothe (64601)
12,438 residents
- 64635 515
Chula (64635)
515 residents
- 64664 350
Mooresville (64664)
350 residents
- 64686 271
Utica (64686)
271 residents
- 64656 240
Ludlow (64656)
240 residents
What this shows Among its immediate neighbors, ZIP 64601 ranks the most populous - useful context the national average alone can't give.
ZIP 64601 vs its nearest neighbors, by median income
Median household income of this ZIP and the closest reporting ZIP codes within ~10 miles.
- 64635
Chula (64635)
$78,333 median income
- 64664
Mooresville (64664)
$73,125 median income
- 64686
Utica (64686)
$71,563 median income
- 64601
Chillicothe (64601)
$63,061 median income
- 64656
Ludlow (64656)
$58,438 median income
What this shows By household income, ZIP 64601 ranks #4 of 5 neighboring ZIPs, local affluence varies block to block, not just metro to metro.
Nationwide ZIPs with similar ACS profiles
Two Census-derived peer sets for ZIP 64601, both outside MO so the neighborhoods are not geographic containment (Nearby and same-county blocks stay local).
Similar population
Nearest cross-state ZIPs by resident population (12,438 here; floor ≥1,000).
Similar median household income
Nearest cross-state ZIPs by ACS median household income.
More ZIP Codes in Livingston County
Related Areas
Frequently Asked Questions
What county is ZIP code 64601 in?
ZIP code 64601 (Chillicothe) is located in Livingston County, Missouri. Livingston County contains multiple ZIP codes, see the full list at /counties/livingston-mo.
What is the population of ZIP code 64601?
ZIP code 64601 in Chillicothe, MO has a population of 12,438 according to the Census Bureau ACS 2023 estimates.
What is the median household income in ZIP 64601?
The median household income in ZIP 64601 is $63,061, which is 17% below the national average of $76,288.
What is the average home value in ZIP 64601?
The median home value in ZIP 64601 is $153,900, which is 45% below the national average of $278,155.
What is the demographic makeup of ZIP 64601?
The largest racial group in ZIP 64601 is White at 90.2%. Hispanic or Latino residents make up 2.2% of the population.
How many businesses are in ZIP code 64601?
ZIP code 64601 has 369 business establishments employing approximately 5,009 people, according to Census Bureau ZIP Code Business Patterns (ZBP) 2023 data.
What are the main industries in ZIP code 64601?
The top industries by establishment count in ZIP 64601 are: Retail trade (61), Other services (except public administration) (44), Health care and social assistance (38). There are 14 industry sectors represented in total.
How have home values changed in ZIP code 64601?
According to the FHFA House Price Index, home values in ZIP 64601 increased by 6.6% in 2024. Since 2000, home values in this ZIP have appreciated by approximately 116%. This is a developmental index based on repeat sales and appraisal data from Fannie Mae and Freddie Mac.
What is the education level in ZIP code 64601?
In ZIP code 64601, 59.5% of residents aged 25+ have a high school diploma or higher, and 18.4% hold a bachelor's degree or higher. These figures come from the Census Bureau ACS 5-Year Estimates (2023).
What is the average commute time in ZIP 64601?
The mean commute time for workers in ZIP code 64601 is 19.3 minutes according to Census ACS data. The national average is roughly 26 minutes, so commuters here spend less time traveling to work than typical.
What percentage of residents own vs. rent in ZIP 64601?
In ZIP code 64601, approximately 70.7% of occupied housing units are owner-occupied and 29.3% are renter-occupied, based on Census ACS 2023 data.
What is the poverty rate in ZIP code 64601?
The poverty rate in ZIP code 64601 is 12.4% according to Census Bureau ACS 2023 estimates. This measures the percentage of the population living below the federal poverty threshold.
Related
Take this with you
What to do with ZIP 64601's numbers, next.
- See how ZIP 64601 compares to a neighboring ZIP code on the same Census fields Compare this ZIP
- Check where Chillicothe, MO ranks among every U.S. ZIP code on income, education, or homeownership View national rankings
- Save this ZIP to your shortlist to track alongside others you're considering View your shortlist
ZIP Code Tabulation Areas (ZCTAs) are Census Bureau approximations of USPS ZIP codes; figures describe the ZCTA area, not any single address within it.